Analysis of Intensive Care Units (ICUs) Blood stream Infections (BSI) in Kafkas University Health Research and Application Hospital

Abstract

Objectives: Sepsis is one of the most important cause of admission in Intensive Care Units, probably due to the more severe illnesses of hospitalized patients and to the persistently high incidence of nosocomial infections. However, despite the availability of potential antibiotics and refined supportive care the mortality of septic patients remains high, with overall estimates of about 30% and increasing to 50% when associated with shock. In this study, our aim is to determine retrospectively the epidemiology of blood stream infections occurred in Intensive Care Units of Kafkas University Health Research and Application Hospital and to present the first data from this university hospital. Materials and Methods: Total 1004 blood culture bottle were sent to Microbiology Laboratory of Kafkas University Health Research and Application Hospital between January 2013 to January 2015. All bottles were placed into Automated BACTEC 9050 Blood Culture System. After the positive bottles were detected by machine, the bacteria were identified and antibiotic susceptibility test were performed by using both BD Phoneix Microorganism Identification System and KirbyBauer Disk Diffusion method. Results: Total 202 positive samples were detected and the biggest part of total positive samples (n:164, 81.2%) were sent by Internal Intensive Care Unit. The identified bacteria were MRCNS (n:67, 33.2%), MSCNS (n:42, 20.8%), MRSA (n:29, 14.3%), E.coli (n:23, 11.3%), MSSA (n:16, 7.9%), P.aeruginosa (n:9, 4.5%), Enterococcus spp (n:9, 4.5%), K.pneumoniae (n:4, 1.9%), A.baumannii (n:1, 0.5%), Proteus mirabilis (n:1, 0.5%), Stenotrophomonas maltophilia (n:1, 0.5%), respectively. Additionally Extended-Spectrum Beta-Lactamase (ESBL) were detected as positive in 7 E.coli. Conclusions: Gram negative bacteria are still important. However; in recent years, coagulase negative staphylococci are the most detected bacteria in Intensive Care Units. For this reason, increased MRCNS rate may restrict antibiotic options and lead increasing the usage of glyco- peptides prophylactically. It is necessary to perform active surveillance studies, obey standard infection control measures and develop an appropriate antibiotic policy for decreasing the frequency of resistant microorganisms, due to the changes in microorganism types in ICUs and their antibiotic susceptibilities.

Authors and Affiliations

Keywords

Related Articles

Bacteriocin Producing Lactobacilli Strains as a Biological Strategy to Control Listerial Growth

Listeria monocytogenes causes listeriosis in humans and animals, and is predominantly transmitted by ingestion of contaminated food. Its severity and high mortality rate make listeriosis a relevant foodborne disease. Cur...

Early Adjuvant Intravenous Vitamin C Treatment in Septic Shock may Resolve the Vasopressor Dependence

Evidence is emerging that intravenous administration of high-doses of vitamin C may have beneficial effect and can be used as adjuvant therapy of severe sepsis and septic shock. The aim of this study was to evaluate the...

A Systematic Review of Invasive Fungal Infection Treatment With Voriconazole And Caspofungin Among Chinese Population

Background: Voriconazole has been available in China for 10 years. In this time, there has been clinical studies published on the Chinese population. Objective: This study aimed to conduct a systematic review for both En...

GC-MS Analysis of Chemical Components of Taxus Chinensis Var. Mairei Seeds

The extracts of petroleum ether, methanol, ethyl acetate and ether from Taxus chinensis var. mairei seeds were analyzed by GC-MS, and relative contents were determined using a normalized method. 56 peaks were obtained fr...

Molecular Detection of blaTEM and blaSHF in Diarrhoegenic Escherichia coli Isolated from Egyptian Children

Introduction: Escherichia coli (E.coli) is a common bacterial pathogen for acute diarrhea in children. The aim of the present study was to determine the prevalence mainly of TEM and SHV-beta lactamase-encoding genes resp...

Download PDF file
  • EP ID EP197160
  • DOI 10.19070/2329-9967- 1500010
  • Views 110
  • Downloads 0

How To Cite

(2015). Analysis of Intensive Care Units (ICUs) Blood stream Infections (BSI) in Kafkas University Health Research and Application Hospital. International Journal of Microbiology & Advanced Immunology (IJMAI), 3(1), 55-59. https://europub.co.uk./articles/-A-197160