Analysis of ovarian reserve markers (AMH, FSH, AFC) in different age strata in IVF/ICSI patients
Journal Title: International Journal of Reproductive BioMedicine - Year 2016, Vol 14, Issue 8
Abstract
Background: The predictive roles of follicle stimulating hormone (FSH), anti-mullerian hormone (AMH) and antral follicle count (AFC) as ovarian reserve markers in women with different age groups are not established well. Objective: This study compares the value of FSH, AMH and AFC at the time of in vitro fertilization (IVF) treatment in different age groups. Materials and Methods: In this cross-sectional study, 103 women aged 20-43 years candidates for IVF/ICSI cycle were recruited. FSH, AMH and AFC on day 3 of menstrual cycle were measured. The relationship of these measured markers with outcome variables (oocytes number, number of frozen/fresh embryo and chemical and clinical pregnancy) was assessed in different age groups (i.e. 20-32, 33-37 and 38-43 years). Results: our results show that age was correlated with clinical pregnancy, oocyte count and fresh and frozen embryo (p<0.001). AMH, AFC and FSH were not correlated with clinical or chemical pregnancy at total population or age subgroups except the significant correlation of AFC with clinical pregnancy at 33-37 years old group. AFC was correlated with oocyte count and the number of fresh and frozen embryos in the ages group 20-32 years. In this age group, AMH was correlated with fresh and frozen embryos. AMH, AFC and FSH were correlated with oocyte count and the number of fresh embryos in age group 33-37 years. AMH was correlated with oocyte count and the number of fresh embryos in 38-43 years old group. Conclusion: We concluded that the age is the superior predictor of IVF outcome and AMH and AFC are variable predicting markers of ovarian reserve in different age groups.
Authors and Affiliations
Ensieh Shahrokh Tehraninezhad, Fatemeh Mehrabi, Raheleh Taati, Vahid Kalantar, Elham Aziminekoo, Azam Tarafdari
Keywords
Related Articles
- EP ID EP185890
- DOI -
- Views 134
- Downloads 0
Types of reproductive disorders in underweight and overweight young females and correlations of respective hormonal changes with BMI
Background: Higher risks of reproductive problems have been found in underweight and overweight women with rapid weight gain or loss but evidence is inconsistent especially in relation to the effect of age of body weight...
Effect of granulocyte colony stimulating factor (G-CSF) on IVF outcomes in infertile women: An RCT
Background: Despite major advances in assisted reproductive techniques, the implantation rates remain relatively low. Some studies have demonstrated that intrauterine infusion of granulocyte colony stimulating factor (G-...
Thymoquinone as a natural spermostatic substance in reproductive medicine: An experimental study
Background: Nonoxynol-9 a nonionic surfactant is widely used for its spermicidal effects. Finding new sperm immobilizing agents is necessary because Nonoxynol-9 damages the tissues of female reproductive system. Objectiv...
Stereological study on the effect of vitamin C in preventing the adverse effects of bisphenol A on rat ovary
Background: Bisphenol A (BPA), an environmental pollutant, can generate free radicals which damages the reproductive system. Vitamin C is an antioxidant which may prevent the adverse effects of free radicals. Objective:...
Polymorphism of MnSOD (Val16Ala) gene in pregnancies with blighted ovum: A case-control study
Background: Blighted ovum is one of the most common reasons for abortion during the first three months of pregnancy. Manganese superoxide dismutase (MnSOD) is an important antioxidant enzyme in the human immune system. T...