Analysis of Pattern of Congenital Anomalies Diagnosed in A Tertiary Care Hospital
Journal Title: PARIPEX-Indian Journal of Research - Year 2016, Vol 5, Issue 12
Abstract
This is a hospital based prospective analysis conducted in the department of obstetrics and Gynaecology, tertiary care government hospital, Chennai during the period Aug 2013 to April 2014.The aim of the study was to find the incidence, pattern of structural congenital malformations, the most common anomaly, its etiology and the role of prenatal USG in its early detection in our population. During the study period 9500 women were admitted for delivery. Since our hospital is a tertiary care centre, all anomalous fetuses referred had an USG done with varying levels of expertise from different centres. All these women were further evaluated and anomalies were confirmed by our in house radiologist. Genetic counselling and early termination of pregnancy was offered to all major lethal anomalies diagnosed. A thorough post-natal screening and examination was performed on all infants born and all anomalies were recorded. The pattern of congenital anomalies found included CNS(25%), CVS (21%), Musculoskeletal( 15%), GIT(4%), Renal/GUT (8%). 40% of the major anomalies were detected prenatally. In 66% of those antenatally diagnosed with congenital anomaly, pregnancy was terminated. This study stresses the importance of a thorough clinical examination of all neonates and an echo when suspected as many women have missed a target scan at level 2 centres. CNS anomalies were the most common anomaly detected. Among CNS defects NTD was the common anomaly detected by USG. Serum folate level was deficient in 35% of the cases with neural tube defects. This study also stresses the need and significance of periconceptional folic acid supplementation, importance of target scan which aid in terminating an anomalous fetus at an earlier gestation thereby reducing perinatal mortality and parental anxiety.
Authors and Affiliations
Dr. Vanitha. V, Dr. Shanthi. S, Dr. S. Usha Rani
Keywords
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