Analysis of the factors related to mortality in patients with primary brain and central nervous system tumors
Journal Title: Chronic Diseases Journal - Year 2018, Vol 6, Issue 3
Abstract
BACKGROUND: The present study aimed to assess the factors associated with the mortality of patints with brain tumor surgery at Be’sat Hospital in Sanandaj, Kurdistan, Iran. METHODS: In this prospectively cross-sectional study, 108 patients diagnosed with brain tumor and followed by a surgery during April to December of 2014 were recruited. Eighteen cases were excluded from the study due to lack of information about their treatment outcomes. Patients’ information including age, gender, tumor type, tumor location, type of treatment, and extent of resection was collected by a checklist. Clinical outcome of the patients in six months after surgery was determined through phone calling to patients. All analyses conducted in SPSS software using logistic regression. RESULTS: Forty-seven (52.2%) of the studied subjects were women. The age of cases ranged from 3 to 83 years with total mean of 43.4 ± 21.9 years. In six months after treatment, 41 (45.6%) of the treated patients died. After excluding 9 children from final analysis and modeling the data by logistic regression, statistically significant associations were observed between death from central nervous system (CNS) tumor and male gender [odds ratio (OR): 5.25, 95% confidence interval (CI): 1.38–21.99], higher age (OR: 1.07, 95% CI: 1.02–1.13), partial vs. total resection (OR: 20.24, 95% CI: 1.21–337.51), and high malignant potential tumors (OR: 14.77, 95% CI: 4.85–45.02). CONCLUSION: The results showed that both demographic (advanced age and male gender) and clinical factors (high malignant potential tumors and partial removal of tumor) related to the worse outcome in patients with primary CNS tumors during six months after surgery.
Authors and Affiliations
Khaled Rahmani, Faramarz Allahdini, Namam Ali Azadi, Mohsen Sokunati, Abdorrahim Afkhamzadeh
Keywords
Related Articles
- EP ID EP422850
- DOI 10.22122/cdj.v0i0.279
- Views 153
- Downloads 0
The Relationship between Spontaneous Abortion among Nurses and Its Related Factors
BACKGROUND: Abortion is the most common complication of pregnancy which occurs in 15% of pregnancies. The aim of this study was to determine the incidence of spontaneous abortion and its related factors among nurses work...
Risk factors for gestational diabetes mellitus in Sanandaj, Iran
BACKGROUND: Gestational diabetes mellitus (GDM) is defined as any degree of glucose intolerance that is detected for the first time during the most recent pregnancy. It can lead to serious complications for mother and in...
Effectiveness of topical Clinda Soap in the treatment of acne vulgaris
BACKGROUND: A variety of drugs can be used for the treatment of acne vulgaris. Every medicine acts against one or some of the mechanisms of the pathogenesis of acne vulgaris. This study was conducted to assess the therap...
Prevalence of glucose-6-phosphosphate dehydrogenase deficiency in the newborns in Sanandaj, Iran
BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a genetic disorder and assessment of newborns with or without this deficiency is an essential component in public health evaluation in different countrie...
Risk assessment of occupational exposure to BTEX in the National Oil Distribution Company in Iran
BACKGROUND: This study evaluated the quantitative, carcinogenic and non-carcinogenic risk of exposure to BTEX using lifetime cancer risk (LCR) and hazard quotient (HQ) in the National Company for Distribution of Petroleu...