Androgen and Androgen Receptor in Kidney Cancer
Journal Title: Nephrology – Open Journal - Year 2015, Vol 1, Issue 2
Abstract
Kidney cancer is one of the top ten most common cancers in men and women. There are four types of kidney cancer, including Renal Cell Carcinoma (RCC), Transitional cell carcinoma, renal sarcoma, and Wilm’s tumor. The most common type of kidney cancers is renal cell carcinoma (RCC), with around nine out of ten kidney cancers being RCC (American Cancer Associate). Epidemiology studies have identified several risk factors associated with kidney cancer.1 Among them, male gender is associated with twice incidence rate of RCC as female.2 Androgen and Androgen Receptor (AR) are major factors contributing to malegender-associated-diseases, such as prostate cancer,3 suggesting that androgen and AR might be involved in RCC development and progression.
Authors and Affiliations
Chiung-Kuei Huang
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