Anti-Diabetic Activity Of Polyherbal Formulation On Alloxan Induced Diabetes.
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2018, Vol 13, Issue 1
Abstract
Diabetes is a metabolic disorder with major complication associated with hyperglycemia, inflammation, foot ulcer, Nerve disorders and sexual depression Plant medicines are readily used in combination rather than in a single form to get maximum benefit from their combined potential. . Therefore a polyherbal suspension containing alcoholic extract of rhizomes of Curcuma caesia, Roxb whole plant of Evolvulus alsinoide ,seeds of Citrullus lanatus , leaves of Gymnema sylvestre, stems of Tinospora cordiofolia, fruits of Withania coagulans and seeds of Caesalpenia bonduc was prepared and evaluated for its antidiabetic activity. Antidiabetic activity was studied in Alloxan induced diabetic rats. The standard drug used was Glibenclamide 10mg/kg. polyherbal suspension at both the doses 400mg/kg bw was having significant activity. The weight gain and decrease in blood glucose level was less than that of standard drug. Thus the prepared oral Polyherbal suspensionis safe for use with promising antidiabetic activity.
Authors and Affiliations
Mahajan S. M. , Baviskar D. T, Chaudhari P. M.
Keywords
Related Articles
- EP ID EP394217
- DOI 10.9790/3008-1301060106
- Views 79
- Downloads 0
A survey of six different water bodies in Port Harcourt municipality for larval stages of dipteran vectors.
Species identification, relative abundance, local distribution, seasonal abundance and similarity index of immature dipteran vectors were investigated from June, 2011 to May, 2012 in six water bodies located in Port Harc...
Heteroside-321 Hepatoregeneration Activity In Cases Of Hepatitis Inducted By Local Hyperthermia
Lipid metabolism and proliferative activity of rat hepatocytes after induction of hepatitis by local hyperthermia and the effect of heteroside-321 on collagen contents and the rate of DNA synthesis in liver and spleen ce...
Phytochemical Screening and Antibacterial/Antifungal Activities of Ginkgo biloba Extract EGb 761
Ginkgo biloba possesses a variety of biological and pharmacological activities. The present study was carried out to evaluate the phytochemical components and antimicrobial activities of Ginkgo biloba extract (EGb 761)....
Dendrochronology Study of Culture Black Pine (Lat. Pinus Nigra) in Area Šumadija (Serbia)
This paper analyzes the importance of monitoring dendrochronology study as indication aspects of the vitality of trees, pine and general culture of pine. The task was processed on the basis of a detailed analysis of blac...
Biosynthesis and characterisation of zinc doped iron oxide nanoparticles from pedalium murex and its new avenues in pharmacological applications
Biosynthesis of metal oxide nanoparticles gains attention over the past decades due to its ecofriendly nature and provides nanoparticles with controlled size and shape. In the present work, zinc doped iron oxide nanopart...