Anti-Diabetic Effect of Occimum Gratissimum on Blood Glucose Level in Alloxan Induced Diabetic Rats
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 2
Abstract
In The Present Study, The Anti Diabetic Effect Of Occimum Gratissimum On Alloxan Induced Diabetic Rats Was Investigated Using Standard Methods. The Result Revealed That The Blood Glucose Levels Of The Rats Were Reduced Following Treatment With The Aqueous Extract Of Occimum Gratissimum. From The Result, At 400mg/Kg, The Blood Glucose Level Reduced Down To 50.0±3.16mg/Dl Compared To Those Treated With Insulin At 99.5±2.69, While At 200mg/Kg, The Blood Glucose Level Was At 105.25±55.54mg/Dl. Those That Were Neither Treated With Occimum Gratissimum Or Insulin Had A Glucose Level Of 108±5.10mg/Dl. The Result Of The Percentage Recovery Rate After Treatment Shows That, At 400mg/Kg, The Recovery Rate Was 84.7 %, 67.2 % At 200mg/Kg And 68.9 % For Those Treated With Insulin. The Result Therefore Revealed The Importance Of The Plant As An Anti Diabetic Agent.
Authors and Affiliations
Ekaiko, M. U, Ndulaka J. C, Ogbonna C. R, Asiegbu E. I4
Keywords
Related Articles
- EP ID EP383536
- DOI 10.9790/3008-1102031214
- Views 62
- Downloads 0
A Preliminary Study on the Species Composition of Vertebrates in Rakchham-Chhitkul Wildlife Sanctuary in Trans-Himalayan Baspa (Sangla) Valley, District Kinnaur, Himachal Pradesh, India
Biodiversity incorporating all the living forms of life is the essence and manifestation of evolutionary history of life on earth. Vertebrates are the most prominent and an important constituent of the biodiversity. Expl...
Genotyping of Human papilloma virus DNA isolated from cervical tissue biopsies of Iraqi women with different cervical abnormalities
Human papillomaviruses(HPV) are the etiological agents of cervical and other ano-genital malignancies. More than 200 genotypes of HPV have been identified, of these, genotypes 16,18,31,33,45,51,52,53,58 have been classif...
Mini Review: Antitumor promotion as the best strategy for chemoprevention
Transformation of normal cell to cancer cell is known to be a multiple step process known as carcinogenesis. A lot of chemopreventive agents have been isolated from plant derived phytocompound reported to exhibit potent...
Antibacterial, Cytotoxic and Analgesic Activities of the Ethanol Extract of Feronia Limonia Linn Fruit Pulp.
The present study was undertaken to explore the antibacterial, cytotoxic and analgesic activities of the ethanolic extract (ET) of Feronia limonia fruit pulp. The pulp of elephant apple was extracted with ethanol by cold...
Influence of Various Dosage Forms on Stability and Corneal Bioavailability of Desloratadine Ophthalmic Preparations
Designing ophthalmic drug delivery system to a target tissue of the eye has become a major challenge for scientists. The aim of the present study was to formulate desloratadine (Des) in different ophthalmic preparations...