Anti-hyperglycaemic activity of Pergularia daemia (Forssk.) Chiov
Journal Title: The Journal of Phytopharmacology - Year 2014, Vol 3, Issue 1
Abstract
Pergularia daemia (Forssk.) Chiov. is commonly known as ‘Velipparuthi’ and its leaves are traditionally used to treat fevers, rheumatism, liver disorders, emetic and expectorant. The present work is aimed to evaluate the effect of leaves of P. daemia on blood glucose level status in streptozotocin induced diabetic rats. STZ diabetic rats showed decreased levels of blood glucose as compared to normal. Daibetic animals were treated with various extract of P. daemia leaves (100, 200 and 300 mg/kg b.w) for 21 days. Oral administration of P. daemia showed the marked reduction in elevated level of serum glucose as compared with diabetic group at a dose of 100, 200 and 300 mg/kg. The results suggested that oral administration of P. daemia possesses significant antidiabetic potential. It was concluded that antidiabetic effect of P. daemia may due to its bioactive compounds responsible for antidiabetic activity present in the leaves extract.
Authors and Affiliations
P. Vinoth Kumar, N. Ramesh
Keywords
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