Anti-inflammatory Activity and In silico Approaches on Root Extract of Decalepis hamiltonii Wight & Arn
Journal Title: Journal of Pharmaceutical Research International - Year 2017, Vol 18, Issue 2
Abstract
Aims: The present study was aimed to evaluate anti-inflammatory and antioxidant potential of methanol root extract of Decalepis hamiltonii. Results: The methanolic extract showed in vitro anti-inflammatory activity inhibition cells 96.1%µg/ml. MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay was significant inhibited by the methanol (96.2) and inhibition addition the Nitric oxide production 25 µg/ml 95% inhibition. The methanol extract of Decalepis hamiltonii shows a Thus, a very strong approach to In-silico docking and in vitro anti-inflammatory study for whole with these compounds/extract. Conclusion: From the study it is concluded that the root extract of Decalepis hamiltonii showing a strong approach to In-silico docking and anti inflammatory activity.
Authors and Affiliations
Palanisamy Prakash, Rengarajan Manivasagaperumal
The Antimalarial Effect and Mechanism of Action of Methanolic Root Extract of Boerhaavia diffusa in Mice
Aims: This study evaluated the antimalarial effect of methanolic root extract of Boerhaavia diffusa and its mechanism of action in Mice. Study Design: One-factor two control groups experimental design. Place and Duratio...
Use of Antimicrobial Medicines among University Students in Sierra Leone
Aims: Misuse of antimicrobial medicines is a major contributory factor to development of resistant strains of micro-organisms, therapeutic failure and increased healthcare costs in many countries. To identify pattern of...
Ciprofloxacin Antibiotics Removal from Effluent Using Heat-acid Activated Red Mud
In this study, the adsorption of Ciprofloxacin (CIP) antibiotics from a synthetic solution containing CIP is investigated using Red Mud (RM) and Red Mud that is activated by HCL (ARM). Scanning Electron Mi...
Bioassay Guided Isolation and Evaluation of the Antidiabetic Principles of Combretum dolichopetalum Root
Aims: The present study was aimed at investigating the antidiabetic potentials of Combretum dolichopetalum root in alloxan-induced animals with the hope of isolating its antidiabetic principles. Study Design: Sixty four...
HPTLC Methods for Determination of Gemifloxacin Mesylate in Rabbit Plasma
Aim: A new, simple, rapid, very sensitive and accurate high performance thin-layer chromatographic (HPTLC) method has been developed and validated for estimation of Gemifloxacin in rabbit plasma. Study Design: Validation...