ANTI-INFLAMMATORY POTENTIAL OF THE AQUEOUS ROOT EXTRACT OF ARISTOLOCHIA RINGENS (VAHL)
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2019, Vol 6, Issue 11
Abstract
This study was carried out to investigate the anti-inflammatory potential of the aqueous root extract of Aristolochia ringens (AR) (10-100 mg/kg p.o). Aqueous root extract of Aristolochia ringens was evaluated for anti-inflammatory potential using standard Carrageenan-induced rat paw oedema model. The activities of the extract at varying doses were compared to indomethacin a standard anti-inflammatory drug. In all the experiment, AR (10-100 mg/kg) significantly (P= 0.05) reduced increase in rat paw size with a peak effect of 57.10% observed by the sixth hour at 25 mg/kg. This is comparable to the 57.90% reduction by indomethacin (10 mg/kg) at the fourth hour, by which time AR (50 mg/kg) produced a comparable 52.60%. This results show that the aqueous of Arisolochia rigens possesses anti-inflammatory potential. It is therefore advisable that the use of this extract in herbal medicine should be encouraged.
Authors and Affiliations
Dr. Akinlami Omokehinde Oseni
Keywords
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