ANTI- MICROBAL EFFICACY OF MEDICINALLY IMPORTANT PLANTS (C. PHLOMIDIS) USED IN FOLKARIC MEDICINES IN ARID ZONE
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 5
Abstract
The present investigation was undertaken to evaluate in vivo antimicrobial activity of different extracts (Methanol, Benzene and Aqueous) of Clerodendrum phlomidis plants parts. In vivo antimicrobial efficacy of various extracts of Clerodendrum phlomidis was assessed by disc diffusion method against Gram positive - Bacillus subtilis (ATCC 6633), Staphylococcus aureus (ATCC 25923) Gram negative- Escherichia coli (ATCC 25922), Psedomaonas aeruginosa (ATCC 27853) and fungal strains Aspergillus niger (ATCC 16404), Aspergillus flavus (ATCC 9807), Candida albicans (ATCC 5027) and Candida glabrata (ATCC 66032). The methanol leaf extract exhibited highest zone of inhibition against the bacterial stain in S. aureus (15.6±0.6mm) with low MIC values (0.078 mg/ml) and in the case of fungal strains C. albicans (14.0±0.0mm) with low MIC values (0.156 mg/ml).However, none of activity is shown by aqueous extract against pathogenic bacteria. Result of the present investigation indicates that Clerodendrum phlomidis possess compounds with antimicrobial properties and hence can be exploited for future natural plant based antimicrobial agents.
Authors and Affiliations
Jasvinder Kaur, Renu Sarin
Keywords
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