Anti-oxidant and Anti-inflammatory Activity of Cassia auriculata (Flowers)
Journal Title: Journal of Pharmaceutical Research International - Year 2015, Vol 8, Issue 1
Abstract
Aim: To analyze the antioxidants and anti-inflammatory potential of ethanolic crude extract of Cassia auriculata flowers. Study Design: 2 kg of fresh flowers were soaked with 90% ethanol at room temperature (25ºC-30ºC). After 72 hrs the ethanolic extract was filtered. This extract was distilled and finally the crude was obtained. This ethanolic crude to get required concentrations and were used for screening antioxidants and anti-inflammatory activities. Place and Duration of Study: PG & Research Department of Chemistry, Periyar E.V.R. College (Autonomous), Trichy, Tamilnadu, India. During the month of August and September 2014. Methodology: Fresh flowers of Cassia auriculata were extracted with ethanol and evaluated for antioxidant activities by 2,2-Diphenyl 1-picryl hydrazyl solution (DPPH), 2,2'-azino-bis(3-ethylbenzthiazoline-6-sul- phonic acid (ABTS) assay and anti inflammatory activites by humen blood cell (HRBC) membrane stabilization method and Inhibition of albumin denaturation method. Results: The results obtained showed that the ethanolic crude extract of Cassia auriculata flowers can be considered as good sources of anti-oxidants, anti-inflammatory and can be incorporated into the drug formulations. Conclusion: This study justifies the anti-oxidants, anti-inflammatory activity of ethanolic crude extract of Cassia auriculata Flowers. Further detailed analysis of this sample is required to identify the presence of bioactive compounds responsible for anti-oxidants, anti-inflammatory activities. Studies are highly needed for future drug development.
Authors and Affiliations
N. Muruganantham, S. Solomon, M. M. Senthamilselvi
Keywords
Related Articles
- EP ID EP344274
- DOI 10.9734/BJPR/2015/18059
- Views 104
- Downloads 0
Gender Variation Studies in Dermatoglyphic Patterns (Level 2 Details) of the Ikwerre Ethnic Group in Rivers State, Nigeria
Background to the Study: Dermatoglyphics have had several definitions but each boils down to a simple sentence ‘act, process or science of studying ridge patterns on the skin of the palm, fingers, foot and toes of primat...
Identification of Phenolic Compounds in Hibiscus sabdariffa Polyphenolic Rich Extract (HPE) by Chromatography Techniques
The study was designed to determine the phenolic constituents of Hibiscus sabdariffa polyphenolic rich extract (HPE), (a group of phenolic compounds occurring in the dried calyx of the red variety of Hibiscus sabdariffa)...
Animal Model for Hypoglycemic Studies Using Albino Rats
Introduction: It could be speculated that hypoglycemia increases level of serum α-amylase and α-glucosidase and their corresponding mRNA, with concomitant increase in plasma level of glucagon. However, the concept of dev...
Possibilities of Developing New Formulations for Better Skin Protection from a Traditional Medicinal Plant Having Potent Practical Usage
Aims: Natural products obtained from different types of plants have made an important impact since ancient times throughout Asia. Since wood of Hesperethusa crenulata (Roxb.) Roem has been used traditionally by women in...
Strong Protein Glycation Inhibitory Potential of Clove and Coriander
Aims: Protein glycation mediates almost all chronic diabetic complications associated with hyperglycaemia. In view of searching for safe antiglycating agents from nature, the protein glycation inhibitory potential of thr...