Antibacterial Activity of Methanolic Fruit Extract of RandiadumetorumLamk against Ocular Pathogens
Journal Title: Saudi Journal of Medical and Pharmaceutical Sciences - Year 2018, Vol 4, Issue 6
Abstract
Abstract:Ocular diseases have been documented as the most common health problems universally. Most of the chemicals and synthetic drugs currently in use have marked side effects. Hence, there has been an ideal shift from the use of modern drugs to the age old herbs. RandiadumetorumLamk is one such important plant with various established medicinal properties. The aim of the present study was to evaluate the preliminary antibacterial activity of methanolic extract of RandiadumetorumLamk. (Xeromphisspinosa Thumb) Against common ocular pathogens such as Serratiamarcescens, S. agalactiae, Corynebacteriummacbinleysand Propionibacterium acnes. Methanolic extract of the dried fruits of the plant was prepared. Different concentrations of the dried fruit extracts (R. dumetorum) were transferred to the nutrient agar plates, which had been previously inoculated with the test microorganisms. The plates were incubated at 37°C for 24 h in an incubator and the zones of inhibition were measured using well diffusion method. The extract showed potential antibacterial properties comparable with that of the standard streptomycin against the organisms tested. The methanol extract of R. dumetorum displayed a concentration related antibacterial activity. The results showed that the inhibition of the bacterial growth was more pronounced on Corynebacteriummacbinleysas compared to the other tested organisms. Keywords:RandiadumetorumLamk, antibacterial activity, Serratiamarcescens, S. agalactiae, Corynebacteriummacbinleysand Propionibacterium acnes.
Authors and Affiliations
GadilaDhana Sri
Keywords
Related Articles
- EP ID EP397659
- DOI -
- Views 114
- Downloads 0
Evaluation of Cell Block Technique as a Mandatory Diagnostic Tool for Serous Effusions
Abstract:The accurate morphological identification of the cells is a diagnostic problem in conventional smears. By using 10% alcohol formalin as a fixative and obtaining cell block gives effective diagnosis regarding cel...
Prevalence of musculokseletal pain among dentist: a cross-sectional study
Abstract: Around the globe, occupational-related diseases are widespread and common. Posture during work and duty hours are the major risk factor in the development of musculoskeletal disorder. The rationale behind the s...
Primary ovarian large b-cell lymphoma: a case report
Abstract:The involvement of the ovary by malignant lymphoma is a well-known late manifestation of disseminated nodal disease. Primary ovarian lymphoma is rare. We report a case of primary ovarian non-Hodgkin’s lymphoma w...
Deafness Management in Children with the Charge Association
Abstract:The acronym CHARGE is used to describe specific congenital birth defects in children: Colobomata, Heart defect, Atresia of the choanae, Retarded growth or development, Genital hypoplasia, and Ear anomalies or de...
Pharmacognosticand Phytochemical Evaluation of Gynocardia odorataLeaves
Abstract: According to WorldHealth Organization (WHO) medicinal plant is any plant which, in one or more of its organ, contains substance that can be used for therapeutic purpose or which is a precursor for synthesis of...