Antibacterial activity of Momordica charantia (Curcubitaceae) extracts and fractions
Journal Title: Journal of Basic and Clinical Pharmacy - Year 2011, Vol 2, Issue 1
Abstract
Momordica charantia L. belongs to the family Curcubitaceae and it is very common in many Brazilian regions. The plant is a liana with flowers and yellow fruits that present red seeds when are ripe. Popularly known as “melão-de-sãocaetano”,“melão amargo” or “cabaço-amargo”, it possesses many uses: antidiabetic, antihelmintic, antmicrobial, anticancerigenous and antioxidant. The phytochemical prospection of the fresh and dried leaves extracts showed the presence of different classes of secondary metabolites, as flavonoids, alkaloids and tannins, that have demonstrated antimicrobial action. Fresh and dried leaves presented significantly antimicrobial activity against all bacterial strains tested, specially Escherichia coli. Ethyl acetate fractions were effective against Escherichia coli and Bacillus cereus. The modulatory activity was significative too.
Authors and Affiliations
José Galberto Costa, Eidla Nascimento, Fabiola Rodrigues, Adriana Campos
Keywords
Related Articles
- EP ID EP160999
- DOI -
- Views 105
- Downloads 0
Antibacterial activity of Momordica charantia (Curcubitaceae) extracts and fractions
Momordica charantia L. belongs to the family Curcubitaceae and it is very common in many Brazilian regions. The plant is a liana with flowers and yellow fruits that present red seeds when are ripe. Popularly known as “me...
Evaluation of Anthelmintic Activity of Pistia stratiotes Linn.
The ethanolic extract of the plant Pistia stratiotes (Araceae) was investigated for activity against Indian earthworms Pheretima posthuma and nematode Ascardi galli. Various concentrations (10, 20, 50 mg/ml) of ethanolic...
ARE THE OPTIMUM PHARMACEUTICAL PREPARATIONS USED FOR THE SECOND-LINE ERADICATION THERAPY FOR HELICOBACTER PYLORI INFECTION IN JAPAN? - A DISCUSSION FROM A SIMULATION FOR THE AMOUNT OF ANTIBIOTICS IN STOMACH BASED ON THE DATA OF DISSOLUTION STUDIES -
The purpose of this study was to evaluate whether the optimum preparations are used for the second-line eradication therapy for Helicobacter pylori (H. pylori) infection in Japan. In the therapy, commercial tablets, whic...
AN OVERVIEW OF NUTRACEUTICALS: CURRENT SCENARIO
Using food products to promote health and cure disease is renowned.Currently, most of the drug molecules available in the formulations were ancientlyused in their crude form. Dr Stephen De Felice first coins the te...
Hepatoprotective effect of leaves of Peltophorum pterocarpum against paracetamol Induced acute liver damage in rats
The 70% ethanolic extract of Peltophorum pterocarpum leaves were investigated for its hepatoprotective effect against paracetamol induced acute liver damage on albino wister rats. Paracetamol (2gm/kg, po) significantly e...