Antibacterial activity of Momordica charantia (Curcubitaceae) extracts and fractions
Journal Title: Journal of Basic and Clinical Pharmacy - Year 2011, Vol 2, Issue 1
Abstract
Momordica charantia L. belongs to the family Curcubitaceae and it is very common in many Brazilian regions. The plant is a liana with flowers and yellow fruits that present red seeds when are ripe. Popularly known as “melão-de-sãocaetano”,“melão amargo” or “cabaço-amargo”, it possesses many uses: antidiabetic, antihelmintic, antmicrobial, anticancerigenous and antioxidant. The phytochemical prospection of the fresh and dried leaves extracts showed the presence of different classes of secondary metabolites, as flavonoids, alkaloids and tannins, that have demonstrated antimicrobial action. Fresh and dried leaves presented significantly antimicrobial activity against all bacterial strains tested, specially Escherichia coli. Ethyl acetate fractions were effective against Escherichia coli and Bacillus cereus. The modulatory activity was significative too.
Authors and Affiliations
José Galberto Costa, Eidla Nascimento, Fabiola Rodrigues, Adriana Campos
Keywords
Related Articles
- EP ID EP160999
- DOI -
- Views 113
- Downloads 0
Evaluation of Anthelmintic Activity of Pistia stratiotes Linn.
The ethanolic extract of the plant Pistia stratiotes (Araceae) was investigated for activity against Indian earthworms Pheretima posthuma and nematode Ascardi galli. Various concentrations (10, 20, 50 mg/ml) of ethanolic...
Phytochemical analysis and hepatoprotective properties of Tinospora cordifolia against carbon tetrachloride-induced hepatic damage in rats
The present study was conducted to evaluate the hepatoprotective activity of different extracts of Tinospora cordifolia against carbon tetrachloride (CCl4) induced liver damage in rats. The pet ether, ethanol and aqueous...
AN ANTIOXIDANT POTENTIAL OF HYDROMETHANOLIC EXTRACT OF URTICA PARVIFLORA ROXB.
Antioxidant activity of hydromethanolic extract of Urtica parviflora Roxb.(family Urticaceae) was investigated by different in vitro methods, namely, nitric oxide scavenging, DPPH scavenging, and reducing power assay. In...
RAPID RP HPLC METHOD FOR QUANTITATIVE DETERMINATION OF LORNOXICAM IN TABLETS
The objective of the study was to develop a simple, rapid, specific and precise reverse phase high performance liquid chromatographic method for the determination of lornoxicam in bulk and pharmaceutical preparations. Ch...
PROTECTIVE EFFECT OF HESPERIDIN ON CARDIOVASCULAR COMPLICATION IN EXPERIMENTALLY INDUCED MYOCARDIAL INFARCTION IN DIABETES IN RATS
Present study was designed to evaluate effect Hesperidin on Cardiovascular Complication in isoproterenol induced myocardial infarction in normal and Streptozotocin-Nicotinamide induced in diabetic rats. Hesperidin (100 m...