Antibiotic consumption pattern in a single neonatal care unit

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Antibiotic consumption pattern in a single neonatal care unit

Journal Title: Family Medicine & Primary Care Review - Year 2013, Vol 15, Issue 4

Abstract

Background. Current and detailed knowledge of antibiotic use is essential in order to implement strategies for reducing the overuse and misuse of antibiotics and the spreading of resistant microorganisms. Objectives. The objective of the present study was to assess antibiotic consumption in the Special Neonatal Care Unit (SNCU ) in a single district secondary level hospital in Warsaw (Poland) in 2011. Material and methods. Data on the quantitative and qualitative use of antibiotics was reported by the hospital’s pharmacy. Antibiotic usage was calculated in daily defined doses (DDD s) per 100 patient days and DDD s per 100 admissions according to the Anatomical Therapeutic Chemical Classification (ATC ) System. The antibiotics were ranked by volume of DDD s and the number of antibiotics that accounted for 90% and 100% of the total volume, DU 90% and DU 100% respectively (where DU stands for drug use). Results. 15 antibiotics were used for treatment and prophylaxis at the SNCU , DU 90% was 5 (ampicillin, amoxicillin with clavulanic acid, amikacin, gentamicin and ceftazidime). The total antibiotic use was 28.9 DDD s per 100 patient days (352.17 DD s/100 admissions). Penicillins were the most commonly prescribed antibiotics (80.6%), followed by aminoglycosides (12%). The cost of penicillins and aminoglycosides accounted for 60.2% of the total antibiotic costs. The cost of third generation ephalosporins (18.6%) and meropenem (12.2%) was also respectively high. Conclusions. Presented data indicate high antibiotic consumption in the SNCU and may serve as a background for comparisons with other hospital wards in Poland and other countries

Authors and Affiliations

Aneta Nitsch-Osuch, Anna Marciniak, Katarzyna Życińska, Kazimierz Wardyn

Keywords

antibiotics consumption neonatal unit

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EP ID EP94803
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