Antibiotic susceptibility pattern of bacterial uropathogens isolated from patients at a tertiary care hospital
Journal Title: Indian Journal of Microbiology Research - Year 2017, Vol 4, Issue 3
Abstract
Background: Urinary tract infection (UTI) is one of the most common infections in both outpatients and hospitalized patients. The increasing prevalence of antimicrobial resistance is a major health problem & is associated with high morbidity & mortality. Objectives of the study: 1. To analyse the antimicrobial resistance pattern of uropathogen during a period of 6 month in patients of UTI. 2. To know the prevalence of uropathogens. Materials and Method: A prospective study was conducted on urine specimens suspected to be having urinary tract infection between July 2016 and December 2016 received at Department of Microbiology, SIMS Shimoga. Fresh midstream urine samples were aseptically collected in sterile containers and plated on Blood agar & MacConkey agar plates using a standard loop technique & the growth was processed by standard bacteriological technique. Antimicrobial sensitivity testing was done using Kirby-Bauer methods on Mueller-Hinton agar. Results were interpreted as per the CLSI guidelines. Result: Out of 510 samples 250 samples showed significant bacteriuria. Most common uropathogen isolated was Escherichia coli 61. 6%(154/250) followed by Staphylococcus aureus 19. 2%(48/250), Enterococcus species 10%(25/250), Klebsiella species 3. 2%(8/250), Pseudomonas species 1. 2%(3/250), CONS 0. 8%(2/250). Gram negative organisms were highly sensitive to Fosfomycin, Nitrofurantoin, Imipenam and highly resistant to Norfloxacin, Ciprofloxacin, Levofloxacin. Gram positive organisms were highly sensitive to Linezolid, Vancomycin, Fosfomycin, Nitrofurantoin and least sensitive to Norfloxacin, Ciprofloxacin, Amoxyclavulanic acid. Conclusion: This study showed that high resistance was observed for commonly used antibiotics. Fosfomycin and Nitrofurantoin were the most sensitive drug for gram negative organisms mainly E. coli which is the most common uropathogen isolated.
Authors and Affiliations
Vijetha Sajjanar, D. E. Premlatha, Halesh L. H.
Keywords
Related Articles
- EP ID EP295537
- DOI 10.18231/2394-5478.2017.0075
- Views 99
- Downloads 0
A hospital based survey for rickettsioses in Shimoga, Karnataka using the Weil-Felix test
Background: Members of the genus Rickettsiae are transmitted by ticks, mites and lice to humans. The rickettsial agents are important causes of fever. Clinical diagnosis of rickettsial fevers is difficult and laboratory...
Microbial etiology of acute gastroenteritis in pediatric patients in Western India
Introduction: Acute gastroenteritis is a major cause of illness and death among infants and young children worldwide. According to the World Health Organization (WHO), an estimated 2.5 billion cases of diarrhea occur amo...
A clinicomycological study of dermatophytic infection in a tertiary care hospital
Introduction: Dermatophytosis is a mycotic infection of the hair, skin or nails. Although dermatophytic infection doesn’t cause mortality, it can lead to morbidity and result in a major public health issue usually in tro...
Incidence of multiple drug resistant Bacillus cereus in some popular snacks and sweets sold in Kolkata city, India
Background: Snacks and sweets from road side eateries are cheap sources of nutrition but occasionally cause numerous public health hazards most importantly gastroenteritis. Various factors including poor infrastructure t...
Seroprevalence of Rubella among Female Healthcare Students in a tertiary care teaching hospital
Introduction: Rubella is a disease caused by Rubella virus which can affect anyone of any age and is generally a mild disease, rare in infants or those over the age of 40. Rubella is notorious for causing congenital rube...