ANTIBIOTICS NANOSUSPENSION: A REVIEW
Journal Title: Journal of Drug Delivery and Therapeutics - Year 2017, Vol 7, Issue 2
Abstract
Nanosuspensions are colloidal dispersions and biphasic system consisting of drug particles dispersed in an aqueous vehicle in which the diameter of the suspended particle is less than 1μm in size. Many drugs including antibiotics are having poor solubility. Nanosuspensions have proven to be a better alternative over other approaches currently available for improving bioavailability of such drugs with low solubility. This review describes the methods of pharmaceutical nanosuspension of antibiotic formulations and pharmaceutical applications in drug delivery.
Authors and Affiliations
Merin Mathew
PREVALENCE OF POTENTIALLY INAPPROPRIATE MEDICATIONS IN AYDER REFERRAL HOSPITAL, TIGRAY REGION, NORTHERN ETHIOPIA: PROSPECTIVE STUDY
Background: Potentially inappropriate medication (PIM) use includes the use of drugs with higher risk where adverse drug effect outweighs the clinical benefit, especially when more effective alternative therapy is availa...
HEPATOPROTECTIVE ACTIVITY OF MAHONIA LESCHENAULTII TAKEDA. (ROOT WOOD AND ROOT BARK) ON COUNTRY MADE-LIQUOR (CML) INDUCED HEPATOTOXICITY IN RATS
The hepatoprotective potential of Mahonia leschenaultii Takeda. (root wood and root bark) extract was evaluated in Country-Made Liquor (CML)-induced hepatotoxicity in Wister rats. The rats were made hepatotoxic by admini...
DEVELOPMENT OF CLARITHROMYCIN GASTRORETENTIVE MICROSPHERES
Gastroretentive microspheres of clarithromycin were prepared on the principle of cation induced gelification using sodium alginate and pectin. These microspheres were investigated for micromeritic properties, drug entrap...
NANOPARTICLES CARRYING NATURAL PRODUCT FOR DRUG DELIVERY
Camptothecin, Doxorubicin, Paclitaxel, Vincristine, and Etoposide are the naturally occurring anti-cancer drugs that are analyzed in this analysis. It is found that these compounds can be developed as nanomedicine. It ha...
BILOSOME: A BILE SALT BASED NOVEL CARRIER SYSTEM GAINING INTEREST IN PHARMACEUTICAL RESEARCH
The human body has long provided pharmaceutical science with biomaterials of interesting applications. Bile salts (BSs) are biomaterials reminiscent of traditional surfactants with peculiar structure and self-assembled t...