Anticaries activity of ethanolic extract from ant-nest plant (Myrmecodia Pendens Merr. & L.M Perry) against hyaluronic acid resistant Streptococcus mutans
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2018, Vol 8, Issue 5
Abstract
Background: Streptococcus mutans is known as primary microorganism in the formation of dental plaque and tooth decay. Aims and Objectives: To determine the antibacterial activity of ant-nest plant ethanol extract to inhibit S. mutans clinical isolates growth in vitro. Materials and Methods: The ethanol extracts obtained from the ant-nest plant were studied for antibacterial activity against cariogenic S. mutans obtained from patients with clinically identified carious lesions, using the agar diffusion method. Chlorhexidine gluconate was using as a comparative drug. The simplisia of ant-nest plant was extracted using a maceration method. The phytochemical screening was taken using standard methods. The minimum inhibitory concentration (MIC) test was performed by a macrodilution method and following by subculturing the overnight result onto the surface of agar media. Results: Phytochemical screening of ant-nest plant ethanol extract revealed the presence of polyphenols, flavonoids, tannins, and saponins. The extract showed intensive activity and totally inhibited the growth of S. mutans clinical isolates at 1.25% w/v. In comparison, the chlorhexidine gluconate, essential oil of plants and povidone-iodine in a ranged tested concentration also had given inhibition effect to all hyaluronic acid resistant S. mutans isolates. Conclusion: It can be reasoned that the ethanolic extract of ant-nest plant gave potent and direct antibacterial effect on S. mutans
Authors and Affiliations
Sri Agung Fitri Kusuma, Sulistiyaningsih Sulistiyaningsih, Devita Fauzia
Keywords
Related Articles
- EP ID EP489564
- DOI 10.5455/njppp.2018.8.0102827012018
- Views 69
- Downloads 0
tudy of gender variation in muscle function among young adults
Background: Muscles are the only tissue in the body that has the unique ability to contract which helps in movement of other body parts. Physical activity is one of the important factors which affect the skeletal muscle...
Effect of rice mill dust on peak expiratory flow rate among rice mill workers of Mysore district
Background: Inhalation of different pollutants exposed from the industries cause damage to the membrane structure and mechanical efficiency. This leads to an alteration in the functional properties of the lungs resulting...
Antibacterial activity test of dayak onions (Eleutherine palmifolia L. Merr.) ethanolic extract against Shigella dysenteriae ATCC 13313
Background: Acute bloody diarrhea, which is also called dysentery, is damaged of the intestinal mucosa, sepsis, and malnutrition. Shigella bacteria cause 50% of cases of dysentery; it is due to its ability to produce shi...
Classical autonomic function tests in patients with type 2 diabetes mellitus and healthy volunteers: A comparative study
Background: The incidence of autonomic dysfunction has increased in the presence of type 2 diabetes mellitus and various tools have been developed for assessing it. Classical autonomic function tests are one among...
Effects of filgrastim on gene expression of cholinergic system in the rat hippocampus
Background: Filgrastim is a granulocyte colony-stimulating factor (G-CSF), which also showed effects on memory and cognation. Although recent studies have begun to explore G-CSF-related mechanisms of action in memory, li...