ANTIDIABETIC ACTIVITY AND PHYTOCHEMICAL INVESTIGATION ON THE WHOLE PLANT OF COMMELINA BENGHALENSIS LINN. IN MALE ALBINO RAT.
Journal Title: Journal of Drug Delivery and Therapeutics - Year 2016, Vol 6, Issue 2
Abstract
Study of phytochemical and antidiabetic activity on the whole plant of Commelina benghalensis in male albino rat. The methanolic extract of the whole plant of Commelina benghalensis (100, 200, 400 mg/kg i.p.) has shown significant antidiabetic activity in alloxan-induced diabetic rat. In addition the extract significantly reduced the elevated level of blood cholesterol (p< 0.01) and triglyceride (p< 0.05). At the same dose level, the extract significantly improved the alloxan-induced reducation of blood protein (p< 0.01) to normal value. Keywords: Antidiabetic activity, Commelina benghalensis, male albino rat
Authors and Affiliations
Keywords
Related Articles
- EP ID EP487556
- DOI 10.22270/jddt.v6i2.1200
- Views 84
- Downloads 0
POTENTIAL APPLICATION OF DENDRIMERS IN DRUG DELIVERY: A CONCISE REVIEW AND UPDATE
This review gives concise information about the application of dendrimers in the field of drug delivery. Due to their unique architecture these have improved physical and chemical properties. Due to their terminal groups...
Unifying Mechanism Involving Physiological Activity of Spices: Electron Transfer, Reactive Oxygen Species, Oxidative Stress, Antioxidants, Redox Chemistry, and Foods
This review deals with mode of action of spices. Those studied, involving principal ones and parent substances, together are the following; capsaicin (pepper, tabasco, jalapeño), curcumin (tumeric, ginger, curry), aneth...
A PROMISING TECHNIQUE TO IMPROVE THE SOLUBILITY BY LIQUISOLID COMPACTION TECHNOLOGY
About 60-70% of the drugs synthesized are poorly soluble and comes under BCS Class-II&IV. Now it is a challenging situation during the development of different dosage forms for pharmaceutical industries because solubilit...
LAXATIVE ACTIVITY OF HYDROALCOHOLIC LEAVES EXTRACT OF PUTRANJIVA ROXBURGHII.
Background: This study was aimed to assess the possible laxative effect of roxburghii hydroalcoholic leaves extract of Putranjiva in albino’s Wistar rats. Method: Rats were divided in 5 groups of 6 animals each, I gro...
SOLUBILITY ENHANCEMENT OF EFAVIRENZ (BCS CLASS II DRUG) BY CYCLODEXTRIN INCLUSION COMPLEX TECHNIQUE
The solubility of BCS class II drugs can be enhanced using inclusion complex techniques. Cyclodextrin (CD) and its derivatives are promising carrier for the enhancement of aqueous solubility of drugs. The use of the Knea...