ANTIDIABETIC AND HYPOLIPIDEMIC EFFECTS OF LAPORTEA OVALIFOLIA (URTICACEAE) IN ALLOXAN INDUCED DIABETIC RATS.
Journal Title: African Journal of Traditional, Complementary and Alternative Medicines - Year 2006, Vol 3, Issue 1
Abstract
Laportea ovalifolia (Scham and Thonn) is widly use in Cameroon for the treatment of diabetes mellitus. The present study was designed to evaluate the antidiabetic and hypolipidaemic effects of aqueous extract of Laportea ovalifolia aerial part in normal and alloxan diabetic rats. Diabetes was induced by intraperitoneal injection of alloxan (150 mg kg –1 body weight). The treatment was given for 2 weeks. After the treatment a significant reduction was observed in fasting serum glucose levels in the treated diabetics rats. L. ovalifolia treatment showed considerable lowering of serum total cholesterol, triglycerides, LDL cholesterol, T.C/HDL.C and an increase in HDL cholesterol in the treated diabetic group. These results suggest that the Laportea ovalifolia aqueous extract of the aerial part possesses antidiabetic and hypolipideamic effects in alloxan-induced diabetic rats.
Authors and Affiliations
Claudia Momo, Julius Oben, Dagerbert Tazoo, Etienne Dongo
Keywords
Related Articles
- EP ID EP133831
- DOI -
- Views 112
- Downloads 0
Effects of the hexane extract of <i>mondia whitei</i> on the reproductive organs of male rat
The present study investigates the effects induced by the long term oral administration of the hexane extract of the dried roots of [i]Mondia whitei[/i] at doses of 500 and 1000 mg/kg b.w. on body and organ weights, bioc...
IN VIVO AND IN VITRO ANTI-FERTILITY AND ANTI-IMPLANTATION PROPERTIES OF LEONOTIS OCYMIFOLIA IN RATS
The anti-fertility effect of the aqueous and ethanol extracts of the leaves and roots of Leonotis ocymifolia were studied both in vivo and in vitro. The anti-implantation and anti-fertility activities of the ethanol l...
Traditional medicine development for medical and dental primary health care delivery system in Africa
Traditional African Medicine (TAM) is our socio-economic and socio-cultural heritage, servicing over 80% of the populations in Africa. Although, it has come a long way from the times of our ancestors, not much significan...
Cardiovascular effects of <i>harpagophytum procumbens</i> DC [pedaliaceae] secondary root aqueous extract in some mammalian experimental animal models
In an attempt to scientifically appraise the ‘healing powers’ and medicinal value of Harpagophytum procumbens DC root aqueous extract (HPE), and throw some light on the efficacy and safety of the medicinal plant product,...
Safety of traditional medicines, complementary and alternative medicines in Africa