ANTIDIARRHOEAL ACTIVITY OF PSEUDARTHRIA VISCIDA ROOTS
Journal Title: International Journal of Pharmacy and Technology - Year 2010, Vol 2, Issue 2
Abstract
Aim of study: To evaluate the root extract of Pseudarthria viscida Linn, for antidiarrhoeal activity using standard model. Material and methods: The roots of Pseudarthria viscida Linn were collected from Kolli Hills, dried and extracted with ethanol (95%). Wistar albino rats were used for studies. Castor oil was used to induce diarrhoea and 200, 400 mg/kg of ethanol extract of Pseudarthria viscida (EEPV) was used to test antidiarrhoeal activity. Results were calculated by student âtâ test, to assess statistical significance. Results and Discussion: The extract showed dose dependant inhibition of frequency of defecation as well as reduction in number of wet feces. The percentage inhibitions of faecal with 200 and 400 mg/kg doses of ethanol extract were 48.14 and 62.96 respectively. The plant roots extract contains tannins and flavonoids, which could have contribution to the antidiarrhoeal activity. Conclusion: Ethanol extract of Pseudarthria viscida (EEPV) Linn possesses significant antidiarrhoeal activity.
Authors and Affiliations
Vijayabaskaran M
Keywords
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