ANTIHISTAMINIC AND BRONCHODILATING ACTIVITY OF FRUIT BERRIES OF EMBELIA RIBES
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 10
Abstract
The present study was designed to evaluate the antihistaminic and bronchodilating activity of ethanolic extract of fruit berries of Embelia ribes brum (ER) by using isolated goat tracheal chain preparation and histamine-induced bronchospasm in guinea pigs. In Histamine induced contraction in isolated goat tracheal chain preparation ER inhibited dose dependent contraction of goat tracheal chain produced by histamine. In histamine-induced bronchospasm in guinea pigs, treatment with ER showed significant protection by prolonging Preconvulsion dyspnoea time (PCD). Thus, ER showed anti-histaminic and bronchodilating activity against histamine and hence possesses potential role in the treatment of asthma.
Authors and Affiliations
Anupama Suralkar , Asha Jadhav , Gayatri Vaidya , Kuldeep Gaikwad
Keywords
Related Articles
- EP ID EP156250
- DOI -
- Views 99
- Downloads 0
ANALGESIC ACTIVITY OF THE METHANOLIC EXTRACT OF ALSTONIA SCHOLARIS
The aim of the present study was to investigate the analgesic activity of the methanol extract of the roots of Alstonia scholaris on mice using acetic acid induced writhing and tail immersion test. The analgesic activit...
ENUMERATION OF MICROORGANISMS ASSOCIATED WITH THE DIFFERENT STAGES OF BREAD PRODUCTION IN FUTMIN BAKERY, NIGERIA
Microbiological analysis of different stages of bread which includes dry mixture, non-dry mixture, mixture of ingredient with flour, dough formation, milling, cutting, proofing, baking and cooling stage were obtained fro...
A COMPARATIVE CLINICAL TRIAL OF AMALAKI AND MADHUYASHTI CHOORNA IN AMLAPITTA
Amlapitta can be a result of inappropriate dietary regimen or stress. It is a problem which when left unattended to, results in peptic ulcer and other complications. It is quite a simple problem when it begins, but it ca...
FORMULATION AND EVALUATION OF POSITIVELY CHARGED SELF-EMULSIFYING DRUG DELIVERY SYSTEM CONTAINING IBUPROFEN
One of the most persistent problems faced by the formulation scientists has been to find methods of improving the oral bioavailability of poorly water-soluble drugs. This positively charged SEDDS gives several fold incre...
ANTIBIOTIC SYNERGY TEST: CHECKERBOARD METHOD ON MULTIDRUG RESISTANT PSEUDOMONAS AERUGINOSA
Pseudomonas aeruginosa is a global emergence of multidrug resistant strains leading to a wide variety of nosocomial infections in humans. The clinical use of combination of antibiotic therapy for gram negative infections...