ANTIHYPERLIPIDEMIC ACTIVITY OF DIVYA METHIPACHAK AGAINST TRITON X-100 INDUCED HYPERLIPIDEMIA IN RATS
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 8
Abstract
The present study was designed to evaluate the anti-hyperlipidemic activity of Divya Methipachak a polyherbal formulation against triton induced hyperlipidemia in rats. Hyperlipidemia was induced by Triton X-100 (100 mg/kg, i.p.) and then treated with Atorvastatin (10 mg/kg, p.o) and low and high dose of Divya Methipachak (150 mg/kg and 300 mg/kg, p.o) for 7 days. The effect of treatment was analyzed by quantification of serum lipid profile, blood glucose level and histopathological analysis. The experimental results indicated all the lipid profile such as total cholesterol, Triglyceride, High density lipoprotein cholesterol, Low density lipoprotein cholesterol and the glucose level were restored significantly by all the treated groups compared to triton group. To conclude Divya Methipachak was found to be potential antihyperlipidemic agent in a dose dependent manner in alleviating abnormal conditions induced by triton.
Authors and Affiliations
Seema Setty , Jignasa Patel , Manodeep Chakraborty , Jagadish Kamath
Keywords
Related Articles
- EP ID EP119763
- DOI -
- Views 91
- Downloads 0
A SIMPLE, EFFICIENT AND SOLVENT FREE ONE POT SYNTHESIS OF 3, 3 DIHETEROAROMATIC OXINDOLE
Formic acid catalyzed, single step and environmentally friendly process for synthesis of 3, 3- diheteroaromatic oxindole derivatives is described. This adopted protocol for Friedel- Crafts substitution reaction has the a...
SYNTHESIS OF SILVER NANOPARTICLES BY CHEMICAL REDUCTION METHOD AND THEIR ANTIFUNGAL ACTIVITY
The aim of this study was to evaluate the antimicrobial activity of silvercolloidal nanoparticles which were synthesised by chemical reduction. Silver nanoparticles were synthesized by reduction of silver nitrate with so...
SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS DETERMINATION OF CHLORZOXAZONE AND DICLOFENAC SODIUM IN SYNTHETIC MIXTURE
The present manuscript describes simple, sensitive, rapid, accurate, precise and economical spectrophotometric method for the simultaneous determination of diclofenac sodium and chlorzoxazone in bulk and synthetic mixtur...
MICROBIOLOGICAL ASSAY FOR VITAMIN B
Micronutrients added to foods are analyzed using various procedures depending on their nature and properties. The microbiological assays are better than chemical method because any suitable change in vitamin molecule whi...
EVALUATION OF DIURETIC ACTIVITY OF MILK EXTRACT OF SEMECARPUS ANACARDIUM NUT
Semicarpus anacardium ‘Marketing Nut’ is a tropical flowering plant widely distributed in India. Semicarpus anacardium are widely used for its therapeutic potential as immunomodulatory and in folklore the plant material...