Antimicrobial activity of Foeniculum vulgare Mill essential oil against antibiotic resistance human pathogen
Journal Title: Journal of Biodiversity and Environmental Sciences (JBES) - Year 2014, Vol 4, Issue 7
Abstract
The aim study antimicrobial activity of Foeniculum vulgare Mill essential oil against antibiotic resistance human pathogen. All 36 strains of (12 Klebsiella pneumoniae, 12 E. coli and 12 Staphylococcus aureus) isolated from urine culture of hospitalized patients during the years 2011- 2012. In this study, the essential oil of Foeniculum vulgare Mill obtained by hydrodistillation and the minimum inhibitory concentrations were investigated to characterize the antimicrobial activities of this essential oil. However, overall, E. coli were resistance to 8 of the agent including ceftazidime (50%), tetracyclin (75%), erythromycin (58.3%), cefixime (41.6%) , penicillin (83.3%), ampicillin (58.3%), nalidixic acid (58.3%). Antibiotic susceptibility of K. pneumoniae isolates was evaluated for 4 antimicrobial. However k. pneumoniae were resistance to 4 of the agent including ceftazidime (33.3%) ,cefixime (58.3%), erythromycin (75%), tetracyclin (50%) and S. aureus were resistance to 6 antimicrobial , cefixime (33.3%), trimethoprim-sulfamethoxazol (41.66%), penicillin (50%), oxacillin (83.3%), ceftazidime (66.6%) and vancomycin (8.3%).The highest MIC values of essential oil were found to be 250ppm against four E. coli and three K. pneumoniae and two of MIC value for S.aureus was 10ppm.
Authors and Affiliations
Fereshteh Javadian, Mohammad Ali Mashhadi, Aliakbar Nasiri, Zahra Sepehri, Zohre Kiani, Zahra Shahi
Keywords
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