ANTIMICROBIAL ACTIVITY OF WHOLE PLANT OF LUFFA CYLINDRICA (LINN) AGAINST SOME COMMON PATHOGENIC MICRO-ORGANISMS
Journal Title: International Journal of Pharmaceutical Sciences and Drug Research - Year 2011, Vol 3, Issue 1
Abstract
In this present investigation was to evaluate the antimicrobial activity of pet ether and chloroform extract of whole plant of Luffa cylindrica (Linn) by in-vitro method in agar plate against ten bacterial and four fungal species. The extract was prepared from the whole plant of Luffa cylindrica (Linn) by hot continuous percolation method in Soxhlet apparatus with various solvents (Pet ether & Chloroform). The minimum inhibitory concentration of the various extract range from 266.66µg/ml to 66.66µg/ml on tested bacteria and fungai. The maximum antibacterial activity of chloroform extract of whole plant of Luffa cylindrica (Linn) was found at 200.00µg/ml than that of petroleum ether extract. The significant antifungal activity of chloroform extract was found at 266.66µg/ml than that of petroleum ether extract. The antimicrobial activity was showed at concentration dependent. The results of the above study clearly indicated that the chloroform extract of whole plant of Luffa cylindrica (Linn) was found significant antibacterial and antifungal activity which might be helpful in preventing the progress of various diseases and can be used in alternative system of medicine.
Authors and Affiliations
R. Indumathy, D. Satheesh Kumar, Kolagani pallavi, G. Sashikala Devi
Keywords
Related Articles
- EP ID EP624985
- DOI -
- Views 59
- Downloads 0
IDENTIFICATION OF BIOACTIVE PRINCIPLES OF AVICENNIA OFFICINALIS FRUIT EXTRACT IN METHANOL AND SCREENING FOR ANTIBACTERIAL ACTIVITY
Avicennia officinalis (AO) belongs to family Avicenniaceae. It finds a prominent place in folk medicine. Hence the present work was carried out for the identification of bioactive principles in the fruits of Avicennia of...
TARGETING SEROTONERGIC PATHWAY FOR ANTI-AMNESIC ACTIVITY BY MORUS ALBA L.
The present study aimed to evaluate the anti-amnesic potential of ethyl acetate soluble fraction of methanolic extract of Morus alba L (EASF). The effect of EASF of Morus alba on learning and memory was evaluated by usin...
AMELIORATING EFFECT OF GINGER EXTRACT (ZINGIBER OFFICINALE ROSCOE) ON LIVER MARKER ENZYMES, LIPID PROFILE IN ALUMINIUM CHLORIDE INDUCED MALE RATS
Nowadays, aluminium (Al) exposure has been increasing and it has the potential to be toxic in animal and humans. In recent years, ginger has become a subject of interest because of its beneficial effects on human health....
ANTIANXIETY ACTIVITY OF FRACTIONS AND ISOLATED COMPOUNDS OF VERBENA OFFICINALIS AERIAL PARTS
Verbena officinalis L. (Vervain; family-Verbenaceae) has long been used in the treatment of mental disorders, but not validated systemically for traditional claims. The ethyl acetate fraction (rich in flavonoids) of V. o...
DEVELOPMENT AND IN VIVO EVALUATION OF NELFINAVIR EXTENDED RELEASE TRILAYER MATRIX TABLETS IN THE MANAGEMENT OF AIDS
The purpose of this investigation was to design and develop trilayer matrix tablets of Nelfinavir prepared by direct compression method and consisted of middle active layer with different grades of hydroxypropyl methylce...