Antimicrobial, Antioxidant and Anticancer Activities of Turnera ulmifolia (Yellow Alder) Callus
Journal Title: Journal of Pharmaceutical Research International - Year 2016, Vol 9, Issue 5
Abstract
Aim: The current work aims to study the effect of ethanolic and methanolic extracts of Turnera ulmifolia callus on antimicrobial, antioxidant and anticancer activities. Study Design: The Five grams of leaf derived 30 days old callus powder was soaked in 10 ml of ethanol and methanol overnight and then filtered through Whatman filter paper No. 41 along with 2 gms sodium sulphate to remove the sediments and traces of water in the filtrate. Before filing the filter paper along with sodium sulphate is wetted with ethanol. The filtrate was then concentrated by bubbling nitrogen gas in to solution and reduces the volume to one ml. Place and Duration of Study: Plant Tissue Culture Division, PG and Research Department of Botany, Government Arts College (Autonomous), Coimbatore-641018, Tamil Nadu, India. Methodology: Ethanolic and methanolic callus extracts were evaluated for antimicrobial, antioxidant (DPPH & FRAP) and anticancer activities (MTT assay). Results: The ethanolic and methanolic callus extracts of Turnera ulmifolia showed rich sources of antimicrobial, antioxidants, anticancer and can be incorporated into the drug formulations. Conclusion: This study conformed the use of callus instead of wild plant for herbal medicine. Further studies are needed for isolation and identification of compounds.
Authors and Affiliations
K. Kalimuthu, V. Chinnadurai, R. Prabakaran, P. Subramaniam
Assessment of Mutagenic Effects of Sulfadoxine-Pyrimethamine (SP) on Animal Model
Introduction: The use of medicines in pregnancy has always been a source of concern because of adverse effects on the foetus. Aim: The study therefore investigated the mutagenic potential of sulfadoxine-pyrimethamine (SP...
New Validated Fluorescence Quenching Based Procedure for the Determination of Cilostazol and Clopidogrel in Bulk, Tablets and Biological Fluids, With Application of Stern-volmer Equation
Aims: A very Sensitive, simple and selective Spectrofluorimetric method for the determination of Cilostazol or Clopidogrel through their reaction with fluorescein dye is developed. Determination was performed on raw mate...
Evaluation of the Antioxidant and Analgesic Activities of Hydromethanolic Extract of Chromolaena odorata Leaf
Objective: The aim of the study was to evaluate the analgesic and antioxidant effects of hydromethanolic extract of Chromolaena odorata leaf in rodents. Methods: The antioxidant activities were evaluated using 2, 2-diph...
Thyrotoxic Evaluation and Lipid Peroxidation in Wistar Albino Rats Exposed to Vitellaria paradoxa Stem Bark
Background: Vitellaria paradoxa stem bark is used by villagers because of its antimicrobial activity for treating skin diseases and wound infections in some parts of Nigeria without considering its safety. Aim: The aim o...
Phytochemical Constituents and Biological Activity of Fractions of Stem and Leaves of Acalypha inferno
Aims: Acalypha inferno is an ornamental plant which has been shown to be a phytoremediator of zinc. Other species of this genus used traditionally have been proven to possess pharmacologically active constituents. The st...