Antimicrobial Potential of Dacryodes edulis against Selected Clinical Bacterial Isolates
Journal Title: Microbiology Research Journal International - Year 2017, Vol 19, Issue 5
Abstract
The antimicrobial potential of Dacryodes edulis was investigated to determine the antimicrobial properties of the collected raw D. edulis pulp and seed extracts on some medically important human pathogens. The research was investigated against the selected human pathogens using standard microbiological and biochemical procedures. The D. edulis samples were harvested aseptically between the periods of April to June 2016 from its tree located at IBB way, Calabar Municipality, Nigeria. The aqueous and ethanolic extracts of the seed and pulp at varying concentrations of 1 g/10 ml, 2 g/10 ml, 4 g/10 ml, 5 g/10 ml was tested against some selected human pathogens such as Staphylococcus aureus, Klebsiella pneumonia, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa and Proteus vulgaris. The antimicrobial susceptibility results of the ethanol extracts of D. edulis seed showed marginally higher zones of inhibition to the clinical bacterial isolates tested than the ethanol extract of the pulp tested against the same clinical isolates. The organisms were resistant to the aqueous extracts of both the pulp and seed. The seed ethanol extracts showed a higher zone of inhibition of 21 mm against K. pneumoniae and 18 mm against P. vulgaris as compared to 18 mm as against K. pneumoniae and 17 mm against P. vulgaris showed by Gentamycin used as standard antibiotic control. The result of these has shown that D. edulis could be of immense importance in our nation’s young pharmaceutical industry for the development of new chemotherapeutic agent to address unmet therapeutic needs.
Authors and Affiliations
A. F. Amise, J. A. Lennox, B. E. Agbo
Keywords
Related Articles
- EP ID EP316074
- DOI 10.9734/MRJI/2017/29447
- Views 98
- Downloads 0
Antibacterial and Antioxidant Potential of Leaf and Seed Extracts of Murraya koenigii (Linn.) Spreng
India is known for its rich biodiversity and traditional healers have used flora to cure various human ailments. The same plants are still being used today for the benefit of mankind. Since the beginning of this century,...
A Review of CD4 Positive T Lymphocytes Counts among HIV Positive Patients Attending a Nigerian Teaching Hospital
Aims and Objectives: To determine the baseline CD4 positive T lymphocytes count of HIV/AIDS treatment naïve adults clients presenting for the first time treatment in Benue State University Teaching Hospital. Subjects a...
Effects of Water Activity on the Radial Growth of Aspergillus niger on Solid Medium
The effects of water activity (aw) on the radial growth of Aspergillus niger on Malt Extract Agar was investigated using sodium chloride and glycerol mixtures. Varied concentrations of each solute was used to modify the...
Serum Levels of Immunoglobulin A, G & M in Chlamydia trachomatis Infection among Primary and Secondary Infertility Patients
Background: Chlamydia trachomatis is a well- known sexually transmitted bacteria that is capable of damaging female reproductive tract leading to infertility. Chlamydia trachomatis infection in men can mechanically hinde...
Strain Development of Aspergillus brasiliensis Using Physical and Chemicals Mutagenesis for Possible Overproduction of Xylanase, Amylase, Protease and Cellulase under Submerged Fermentation (SmF)
Aims: Xylanase is commonly involved in the complete hydrolysis of xylan which consisted of hemicelluloses and celluloses as important components of plant cell wall. This enzyme is essential in wide range of applications...