Antimicrobial profile of inducible clindamycin resistant strains of staphylococcus species
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2018, Vol 4, Issue 3
Abstract
Introduction The appearance of continuous resistant to multiple drugs among Staphylococci is a global burden due to its ability to cause severe infections The selective use of drugs is necessary to overwhelm the situation Taking in account present study was carried out to rule out true susceptibility of clindamycin towards staphylococcus species and its antimicrobial profile for judicial use of the drugsMaterial and Methods All the clinical samples received in the Department of microbiology were screened for Staphylococci as per standard guidelines which were further subjected to Antimicrobial susceptibility testing and Dtest to detect MLSb phenotypesResults A total of 421 Staphylococcus species 359853 were Staphylococcus aureus and 62148 were Coagulase negative Staphylococci among them 4210 were Staphylococcus epidermidis 2048 were Staphylococcus saprophyticus Dtest for Saureus shows that 173482 inducible Clindamycin resistant 113315 strains were constitutive MLSb phenotypes and 58162 strains shown to have MSb phenotypes Among CoNS among Staphylococcus epidermidis and Ssaprophyticus 95 5 were Inducible Clindamycin resistance 381 85 were constitutive MLSb phenotypes and 286 10 were MSb phenotypes respectively All the isolates were sensitive to Linezolid Vancomycin and CeftarolineConclusion Inducible clindamycin resistant strains of Staphylococci found to be among half of the strains indicating that true susceptibility of clindamycin should be rule out on routine basis for proper institution of the therapyKeywords Staphylococci MLSb phenotypes AST
Authors and Affiliations
Sunil Hatkar, Sucheta Lakhani, Santosh Kotgire
Keywords
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- EP ID EP485859
- DOI 10.18231/2581-4761.2018.0028
- Views 83
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