Antithyroid Antibodies and Fertility Outcome in Euthyroid Women Undergoing In Vitro Fertilisation
Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 5
Abstract
ABSTRACT Introduction: Antithyroid Antibodies (ATA) are suspected to cause poor outcome of In Vitro Fertilisation (IVF) even in the absence of thyroid dysfunction. Aim: To study the effect of ATA on fertilisation rate, implantation rate and clinical pregnancy rate in euthyroid women undergoing IVF. Materials and Methods: The study was a prospective cohort study conducted at an IVF centre of a Medical College. A total of 81 euthyroid patients planned for IVF were recruited and divided into two groups depending upon the presence of ATA. All of them underwent the standard stimulation protocol. The results were compared using unpaired t-test for continuous variables and Chi-square/Fishers’-exact test for categorical variables. Results: The prevalence of ATA was 20.99% (17/81) in our study population. The fertilisation rate was significantly lower (p<0.05) in women with ATA (66.3% versus 78.9%). However, no statistically significant difference was observed in implantation rate (18.2% versus 26.8%) and clinical pregnancy rate (31.3% versus 39.3%). Conclusion: The presence of ATA was associated with a lower fertilisation rate even in euthyroid state in women undergoing IVF. However, the implantation and clinical pregnancy rate were not correlated with the presence of such antibodies.
Authors and Affiliations
Aheibam Bidya Devi, Sudha Prasad, Bidhan Chandra Koner
Foetal Echocardiography: A Novel Method for Detecting Congenital Heart Disease
ABSTRACT Introduction: Management and outcomes of prenatal and postnatal cardiac diseases have been affected significantly by prenatal detection of foetal Congenital Heart Disease (CHD). Foetal echocardiography plays an...
Midwifery Professionalism: An Integrative Review
ABSTRACT Introduction: In the world today, professionalism has a special meaning and significance in various fields of medical science. Although the professional behaviour of students and midwifery professionals is very...
The South African Dental Schools’ Educational Environment: Final Year Students’ Perceptions at Four Dental Schools
ABSTRACT Introduction: The Educational Environment (EE) can play a major role in the success and progress of students and their studies. The EE includes the infrastructure, clinical activities, the atmosphere created by...
Effectiveness of Shade and Thickness of Resin Cement on the Final Colour of the Porcelain Laminate Veneer: A Scoping Review
ABSTRACT Introduction: Porcelain laminate veneer has evolved as a dependable treatment option due to their superior optical properties similar to natural tooth and exceptional aesthetic outcome. Among the factors which i...
The Semi-automated Software (MyAnkleTM) for Preoperative Templating in Total Ankle Replacement Surgery
ABSTRACT Introduction: MyAnkleTM software is semi-automated digital templating software for total ankle replacement surgery. This software enables a surgeon to review multiple sizes of implant over the radiograph for imp...