Antitumor activity of Leucopyrosinol isolated from the leaves parts of Fluggea leucopyrus
Journal Title: World Journal of Pharmaceutical Sciences - Year 2016, Vol 4, Issue 2
Abstract
The objective of the present study was to evaluate the anti-tumor activity of Leucopyrosinol isolated from the leaves parts of Fluggea leucopyrus. Antitumor activity of Fluggea leucopyrus against EAC was determined using single dose and intermittent treatments over two weeks, i.e. four-drug administration by the intrapretonial route on days, 1, 5, 9, and 11 after EAC cells inoculation. The compound and the vehicle were administered I.P using 10 mice per test group. Results indicated that there was significant increase in life span and reduction in the tumor volume in Fluggea leucopyrus treated mice. The results of the study strongly demonstrate that Fluggea leucopyrus exhibited significant antitumor activity against EAC in mice.
Authors and Affiliations
Dhafer Shaher Shaher
Keywords
Related Articles
- EP ID EP195466
- DOI -
- Views 75
- Downloads 0
Development and characterization of Cassia acutifolia effervescent tablets
Since ancient times Cassia acutifolia plant extract has been used in traditional or herbal medicine. The leaves contain anthraquinone glycosides that have a significant laxative effect. Purposes of this study was extract...
Adsorption behavior of methylene blue onto gellan gum-bentonite composite beads for bioremediation application
Biopolymer Gellan Gum (GG) was made into insoluble composite bead using Bentonite (BT), a clay material. This insoluble composite formation was carried out using ionotropic gelation method where calcium chloride was a cr...
A review of shilajatu based on samhitha and nighantus
Shilajatu, a drug is described in many samhitas and nighantus as an Ayurvedic medicine. Which is an exudation from rock during hot seasons. It is a type of resin that oozes out from the cracks in the layers of the rocks...
Complementary and alternative medicine use in children with haematological disorders
Objectives: To study pattern of complementary and alternative medicine(CAM) use in paediatric patients suffering from thalassemia and compare CAM use in patients of thalassemia and sickle cell disease(SCD). Methodology:...
Study of Dermatophytosis prevalence in Al-Nassiriyah city- Iraq
The present study aimed to investigate the prevalence of some dermatophytes species from patients with dermatophytosis in Thi-Qar Province during the period from August 2014 to January 2015. One hundred eighty samples we...