ANTIULCER ACTIVITY OF MIMUSOPS ELENGI BARK EXTRACTS AGAINST SEROTONIN INDUCED ULCER IN RATS
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 8
Abstract
Ethnobotanical knowledge of medicinal plants is some of the most prominent sources of new drugs and has shown potential results for the treatment of gastrointestinal disorders. In order to establish the pharmacological basis for the ethno medicinal use of Mimusops elengi Linn. In gastrointestinal affections, the effect of bark extracts of Mimusops elengi family Sapotaceae was evaluated in serotonin induced ulceration (20mg/kg) in albino rats. Antiulcer activity was evaluated by measuring ulcer index and percentage of ulcer healing. The alcoholic extract (200mg/kg) and Petroleum ether extracts (200mg/kg) of bark of Mimusops elengi showed significant antiulcer activity as evidenced by the data obtained. The present finding suggests that the alcoholic extract of Mimusops elengi bark have antiulcer property in albino rats.
Authors and Affiliations
Prakash Dabadi , Koti B. C. , Vijay Tikare , Chandrakala , Manjuntha Katagi
Keywords
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