APPLICATION OF CHITOSAN IN THE FORMULATION OF HYDROGELS APPLIED ON SKIN
Journal Title: Progress on Chemistry and Application of Chitin and its Derivatives - Year 2013, Vol 0, Issue
Abstract
These studies concerned the effect of composition on the substrate physicochemical parameters of hydrogels for use on skin. Hydrogels containing 1% of hydrocortisone and 1% of chitosan addition was made on the basis of methylcellulose, sodium carboxymethylcellulose and Carbopol 934 P. The release proceeds according to first-order kinetics. Depending on the type and composition of the polymer gels were obtained with various pharmaceutical availability of hydrocortisone. Addition of 1% chitosan affects the acceleration of the release in any given case
Authors and Affiliations
Jan Meler, Maria Szcześniak, Bożena Grimling, Janusz Pluta
RESEARCH OF PHARMACEUTICAL PROPERTIES OF HYDROPHILIC POWDERS CONTAINING LACTIC ACID COMPLEXED WITH CHITOSAN
Hydrophilic powders passing gels containing lactic acid complexed with chitosan at a stoichiometric ratio of 1:1 and 8:1 revealed pH ranged from 3.92 to 4.44 and 2.36 to 2.84. Rheological studies demonstrated that the re...
THE INFLUENCE OF THE ADDITION OF COLLAGEN ON THE RHEOLOGICAL PROPERTIES OF CHITOSAN CHLORIDE SOLUTIONS
Colloidal solutions of chitosan of crab origin with the addition of collagen obtained from cowhide were studied. Were presents the influence of collagen concentration and the method of preparing the sample on the obtaine...
ADVANCED CELLULOSIC MATERIALS
Aim of the work was to prepare a method of producing chitosan and chitosan-alginate nanoparticles designed for the modification of textile cellulosic products in hygiene and medical application. Spectrophotometry was use...
INVESTIGATION OF FENOFIBRATE DISSOLUTION RATE INCORPORATED ON SOLID DISPERSIONS INTO CHITOSAN
The aim of the study was to investigate the effect of chitosan on the dissolution of fenofibrate incorporated into this polymer carrier. The study investigated fenofibrate in physical mixtures at the drug to polymer rati...
PREPARATION OF MICRO AND NANOSTRUCTURES OF CHITOSAN BY ULTRASONIC COALESCENCE OF W/O EMULSIONS
In the paper, the preeliminary study of chitosan micro and nanospheres precipitation due to two reverse emulsions (W/O) coalescence is described. The composition conditions, which must be filled to obtain stable reverse...