Application of Z-score in retrospective analysis of external quality assessment for nucleic acid testing
Journal Title: Chinese Journal of Blood Transfusion - Year 2025, Vol 38, Issue 2
Abstract
[Objective] To use the Z-scores as a means of evaluating the results of external quality assessment (EQA), so as to improve the quality control management in laboratories. [Methods] Z-scores control charts were plotted based on the feedback results of nucleic acids EQA from the National Center for Clinical Laboratories from 2021 to 2023, and EQA management was conducted using Westgard quality control rules. [Results] In the EQA from 2021 to 2023, the Roche testing system experienced runaway event in the HBV sample minipool testing, while all other items were under control. For KH testing system, runaway events occurred in HCV sample minipool testing and HBV samples resolution, and a warning was issued for the resolution detection of HIV samples, while other items were under control. [Conclusion] The Z-score control chart can achieve continuous monitoring of EQA results, and the use of Westgard quality control rules for quality assessment management can identify the types of errors, which can help enhance the laboratory’s quality management and control capabilities, and ensure the accuracy of laboratory nucleic acid test results.
Authors and Affiliations
Wei WEI, Ying WEI
Keywords
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- EP ID EP760110
- DOI 10.13303/j.cjbt.issn.1004-549x.2025.02.014
- Views 21
- Downloads 0
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