APPLICATIONS OF PROTEOMICS IN ANIMAL MODEL
Journal Title: International Journal of Pharmacy - Year 2011, Vol 1, Issue 1
Abstract
Proteomics is a relatively new approach for understanding the pathology and pathogenesis of various diseases. It has also been used for characterizing the modifications in protein expression during the development of diseases. Proteomics is defined as a scientific approach used to elucidate all protein species within a cell or tissue, and many researchers are taking advantage of proteomic technology to elucidate protein changes between healthy and diseased states. Animal model plays an important role in the proteomics technology to find out biomarkers, for diagnosis, prognosis and treatment of various diseases. There are several animal models used in proteomic studies they are Caenorhabditis elegans (worm), Drosophila melanogaster (fly), Mus musculus (mouse) and Canine. This review shows several applications of animal models in proteomics. Keywords: Proteomics, Animal Models and Canine
EXPLORING SOLID LIPID NANOPARTICLES FOR INTRANASAL ADMINISTRATION OF STREPTOMYCIN
Streptomycin, the foremost class of drugs called aminoglycosides to be discovered is the only antibiotic remedy for tuberculosis. Streptomycin cannot be given orally, but must be administered by regular intramuscular inj...
METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF NEVIRAPINE FROM TABLETS BY RP-HPLC
A reverse phase high performance liquid chromatography method has been developed for the estimation of nevirapine in tablets. The quantification was carried out on the symmetry C18 column, with a mobile phase consistin...
SIMULTANEOUS ESTIMATION OF TELMISARTAN AND AMLODIPINE BESYLATE IN PHARMACEUTICAL DOSAGE FORM BY RP – HPLC
The chromatographic analysis was performed on ODS symmetry C18 column (150 × 4.6 mm, 5 µ particle size) with mobile phase consisting of acetonitrile and phosphate buffer (pH 4.0) in the ratio of 60:40 v/v, at a flow rate...
ASSESSMENT OF COMMUNITY PHARMACIST’S KNOWLEDGE IN THE MANAGEMENT OF CONSTIPATION IN ADULT
The present study was aimed to evaluate the knowledge of community pharmacists in the management of constipation in adult. The study included 103 community pharmacists, who met the inclusion criteria. The study result re...
PHARMACOLOGICAL PROFILES OF BACOPA MONNIERI: A Review
In recent times, the use of herbal products has increased tremendously in the western world as well as in developed countries. One of the important medicinal plants, widely used therapeutically in the orient and becoming...