APPROACH TO THROMBOCYTOPENIA- A CLINICOPATHOLOGICAL STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 37
Abstract
BACKGROUND Thrombocytopenia is defined as decreased number of platelets below 1.0 lakh/μL1and it may be due to one of four causes: Decreased production, increased destruction, bone marrow failure or splenic sequestration.2 Objective- To find out the cause of thrombocytopenia in febrile patients with age, sex distribution and extent of thrombocytopenia. MATERIALS AND METHODS The study was conducted with 500 cases of thrombocytopenia with fever. All the patients with platelet count less than 1.0 lakh/μL were included and clinic pathological correlation was done. Statistical analysis: Simple random sampling, mean and percentage. RESULTS The most common cause for thrombocytopenia was dengue viral infection, 3 followed by other viral infections, malaria and noninfective causes. Maximum number of patients were in the age group of 10-25 years. CONCLUSION Thrombocytopenia is an important pathological indicator of infection like dengue, malaria and sepsis. It is also common in noninfective conditions like alcoholism and malignancies.BACKGROUND Thrombocytopenia is defined as decreased number of platelets below 1.0 lakh/μL1and it may be due to one of four causes: Decreased production, increased destruction, bone marrow failure or splenic sequestration.2 Objective- To find out the cause of thrombocytopenia in febrile patients with age, sex distribution and extent of thrombocytopenia. MATERIALS AND METHODS The study was conducted with 500 cases of thrombocytopenia with fever. All the patients with platelet count less than 1.0 lakh/μL were included and clinic pathological correlation was done. Statistical analysis: Simple random sampling, mean and percentage. RESULTS The most common cause for thrombocytopenia was dengue viral infection, 3 followed by other viral infections, malaria and noninfective causes. Maximum number of patients were in the age group of 10-25 years. CONCLUSION Thrombocytopenia is an important pathological indicator of infection like dengue, malaria and sepsis. It is also common in noninfective conditions like alcoholism and malignancies.
Authors and Affiliations
Gireesh Vishnupant Achalkar, Kusuma Kusuma
Keywords
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- EP ID EP210946
- DOI 10.14260/Jemds/2017/648
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