Appropriate Selection of Segmentectomy for Patients with Early Stage Non-small Cell Lung Cancer
Journal Title: Journal of Oncology and Cancer Research - Year 2017, Vol 1, Issue 1
Abstract
Several randomized-control trials of lung cancer screening, including USA National Lung Cancer Screening Trial (NLST) and Dutch-Belgian Randomized Lung Cancer Screening Trial (NELSON), have explored the value of low-dose CT in detection of lung cancer and found an increase in the detection of early stage lung cancer. Segmentectomy with systemic lymph node dissection rather than wedge resection was preferred for patients with stage IA Non-small cell lung cancer( NSCLC ) when there was a choice of sublobar resection because it is an anatomic resection and provides a lymph node profile. Previously, most studies described segmentectomy as having an equal recurrence-free survival and overall survival in less or noninvasiveness lung cancer with a predominantly ground-glass (non-solid) appearance on CT imaging. Recent evidence suggests that segmentectomy may offer survival outcomes approaching that of lobectomy for lung cancer patients with small solid predominant nodules. Nevertheless, the evidence is currently still limited. We propose that segmentectomy in a solid predominant appearance lung cancer on CT scan should be chosen with stricter indications such as a smaller solid size (≤ 1.7 cm), air bronchogram, and lower SUVmax (≤ 2.5). Large randomized trials are currently in progress to define the clinical role of segmentectomy, and results are eagerly anticipated.
Authors and Affiliations
Juntang Guo, Xiaodong Tian, Chaoyang Liang
Keywords
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- EP ID EP249323
- DOI 10.28967/jocr.2017.01.17005
- Views 121
- Downloads 0
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