Arterial Stiffness Measured by Popmètre® in Patients with Systemic Sclerosis
Journal Title: Journal of Physiology and Pharmacology Advances - Year 2015, Vol 5, Issue 10
Abstract
Systemic sclerosis (SSc) is a connective desease affecting connective tissue and vessels of any caliber. The affect of large arteries appears by a stiffness that can be an element of disease monitoring. The aim of this study was to evaluate the contribution of pOpmètre in the arterial stiffness measurement in patients with SSc. It was a descriptive and prospective study carried out with scleroderma patients and control subjects. Anthropometric measurements were collected and associated to a questionnaire about demographic and clinical data. The finger-toe pulse wave velocity (ft-PWV) measured by pOpmètre® allowed to explore arterial stiffness. Twenty patients and 26 controls were included in our study. Patients had higher heart rate (p = 0.038) and ft-PWV (p = 0.001). The ft-PWV was correlated with age in controls (r = 0.69 ; p = 0.0001) and showed a trend with systolic blood pressure (r = 0.37, p = 0.09) in patients’ group. The pOpmètre®, a simple and practical tool, highlighted an increase in arterial stiffness in patients with SSc by measuring the ft-PWV. It could play a role in this disease monitoring and in prediction of cardiovascular complications.
Authors and Affiliations
A. Ba , M. Touré , V. Ouédraogo , A. K. Sow , S. D. Houndjo , G. Loubano-voumbi , F. B. Sar , L. Guèye
Keywords
Related Articles
- EP ID EP90155
- DOI -
- Views 120
- Downloads 0
Prevention and Control of Cardiovascular Diseases by Drinking Water in Low and Middle Income Countries: a Review
Cardiovascular diseases are leading cause of death worldwide and due to complex socioeconomic condition of peoples governments are looking to reduce risk factors for CVD’s such as soft water. Water is essential source of...
Clinical and Biological Analysis of 149 Patients under Arv Tri-Therapy Treatment (Zidovudine-Lamivudine-Nevirapine) at National Centre of Blood Donors of Abidjan in Côte D’ivoire
In order to assess the effects of antiretroviral drugs on the local population, a descriptive study was conducted on the tri-therapy ZIDOVUDINE-LAMIVUDINE-NEVIRAPINE. The 149 patients studied were selected from the patie...
Pharmacokinetics and Tissue Residues of Levofloxacin in Normal and Aeromonas Hydrophilia Infected Catfish (Clarias Lazera)
The pharmacokinetics of levofloxacin was studied following intravenous and oral (single & repeated) administrations. Following a single intravenous injection of 10 mg/kg.b.wt of levofloxacin in normal catfish (Claria...
Effect of Fenoldopam on Cytosolic Nitric Oxide Production in Pkd1−⁄− Isolated Femoral Arteries in Response to Fluid Shear Stress Ex Vivo
Adult polycystic kidney disease (PKD) is a genetic disease resulted from mutation in polycystin 1 or 2 proved to be co-localized to endothelial primary cilia. Primary cilium is machanosensory organelle senses shear stres...
Relationship and Distribution of ABO, Rh Blood Groups and Hemoglobin Concentration among the Adolescents
Anemia is a global problem and at its worst in developing countries. It is suggested that the oral supplementation of iron is not the best way to correct anemia (especially which are not due to iron deficiency) due to it...