ASSESSEMENT OF ANTI-INFLAMMATORY AND ANTI-ARTHRITIS ACTIVITY OF JATROPHA GOSSYPIFOLIA IN RATS
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 1
Abstract
Objectives: To investigate anti-inflammatory and anti-arthritic activity of latex Jatropha gossypifolia in rodents.Methods: The anti-inflammatory and anti-arthrit activity of latex from Jatropha gossypifolia (JGL) were tested in two different vivo models namely carrageenan induced paw edema in rats and Freund adjuvant arthritis. These models represent acute inflammatory condition and chronic inflammatory condition respectively.Results: The results of the present study showed that latex of JGL possessed remarkable anti-inflammatory activity in carrageenan induced edema (acute model) and antiarthritic activity in CFA induced (subchronic model) arthritis in rats. Conclusion: The latex of the plant Jatropha gossypifolia possesses anti-inflammatory and anti-arthritic activity might be due to its rich flavonoids content.Â
Authors and Affiliations
Arefa S. Ahmad, C T Chopde, Z. N. Kashmiri
Keywords
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