Assessing Proteinuria in Chronic Kidney Disease: Protein- Creatinine Ratio Vs Albumin-Creatinine Ratio
Journal Title: International Journal of Interdisciplinary and Multidisciplinary Studies (IJIMS) - Year 2015, Vol 2, Issue 9
Abstract
Quantification of proteinuria is important in the assessment of chronic kidney disease (CKD).Early detection and treatment for CKD can reduce the progression of kidney disease and its complications like cardiovascular disease. The aim of this study was to find out a better parameter to identify proteinuria(albuminuria) in CKD patients. The study design is a case control study with 50 controls (apparently healthy) with normal urine protein to creatinine ratio (uPCR→0.0-0.3) and normal eGFR and 50 chronic kidney disease(CKD) patients as cases with increased uPCR and decreased eGFR (GFR < 60 mL/min/1.73m2).Urine protein is measured by pyrogallal red method. Urine albumin is measured by immunoturbidimetric assay and urine albumin to creatinine ratio(uACR) is calculated. Data were analysed using SPSS software version 22.0. uACR is found to correlate better than uPCR with eGFR values & uACR has p value < 0.005 and significant. uPCR has p value >0.005 and is not significant.Urine albumin to creatinine ratio(uACR) was found to be superior than urine protein to creatinine ratio(uPCR) to identify proteinuria mainly albuminuria in CKD patients.
Authors and Affiliations
Divya Dharshini B, Ganesh M, Santhi Silambanan
Keywords
Related Articles
- EP ID EP30964
- DOI -
- Views 315
- Downloads 0
The Failure of Implementation of Land Legislations Is a Root Cause of Land Disputes in Cambodia: Case Studies of Beoung Kak Lake and Kampong Speu Sugar Company
Land is a fundamental resource for majority of Cambodian households to generate income and food security. However, recently land has become a hot issue for which land disputes have been risen up rapidly nationwide; yet...
Evaluation of soil fertility status of available N, P and K in Inceptisol of Raipur district of Chhattisgarh
Grid based (GPS) surface (0-15 cm) soil samples by systematic survey were collected from 33 villages and 198 samples (each village six samples) were identified. These soil samples were analyzed for N, P and K and catego...
Holder’s ‘Nation of Cowards’ and the Fallacy ofa Post-Racial America
Former United States Attorney General Eric Holder called the country“a nation of cowards,” in his description of the fear and avoidance from the leaders and the population of a forthright discussion on racism and racial...
Maruti Suzuki Ltd.: Do I Buy or Do I Sell It?
Equity analysis has always been an important part of investments. The main aim of the paper is to analyze the price movements of shares of MARUTI SUZUKI INDIA LTD. and interpret the corrections and trends by using Techn...
Studies on Geochemistry of Sediments in river Kuakhai, Odisha, India
The present study was carried out in the vicinity of Bhubaneswar city, Odisha, India in the year 2012 with six sampling location to assess the geochemistry of sediments of River Kuakhai carrying heavy metals. It was fou...