Assessment of Antimicrobial Utilization and Prescribing Pattern among the Health Care Professionals at a Tertiary Care Rural Teaching Hospital in Southern India
Journal Title: Journal of Pharmaceutical Research International - Year 2014, Vol 4, Issue 10
Abstract
Aims: To monitor the antimicrobial utilization; identify the preferred group of antibiotics in outpatient services, determine the prescribing pattern of antibiotics by consultants in a rural teaching hospital, evaluate the inappropriate usage of antibiotics among population and evaluate the patients knowledge about use of antimicrobials taken for their illness. Methodology: A period of 24 months of investigation is carried out towards prescribing antibiotics and the inappropriate usage of antibiotics among rural population who attended outpatient departments were elicited by Questionnaires survey method and analysed in relation to rational use of antibiotics. The patients were also interviewed for their knowledge regarding drugs, sources, dose, duration and frequency of the drugs. Results: The percentage of distribution of various group of antibiotics in the years of 2009-2010 and 2010-2011 were Sulphonamide (SULP) (4.42%, 1.1%), Penicillin (Pn) (52.4%, 9%), Fluroquinolones (FQs) (24.9%, 44%), Cephalosporins (CPs) (1.2%, 5.2%), Broad spectrum antibiotics (BSA) (3.4%, 3.6%), Macrolide (Mac) (1.3%, 5.2%), Antiprotozoal drug (APD)-metronidazole (12.3%, 12.7%) and fixed dose combination (FDC) (0.2%, 3.6%) respectively. Many practitioners were not aware of Multidrug Resistance (MDR) (50.5%) nor the type of infections (52.6%) or the group of antibiotics (57.9%) exhibiting resistance. Conclusion: Antibiotics are considered as the second most prescribed drugs in the world. In our study, 76.2% were prescribed with antibiotics in their prescription. Analysis of utilization of antibiotics in pharmacy during the year of 2010-2011 revealed a reduction in antibiotic use compared to 2009–2010. Further awareness required to the prescribers and beneficiaries regarding antimicrobial resistance.
Authors and Affiliations
Pitchaipillai Revathi, Thalaimalai Senthinath Jeyaseelan, Madhavan Vigneshwari, Nagarajan Prabhu, Mayilsamy Nithya, Subramaniya Pillai Manickavasagam, Alagappan Uma, Ponniah Thirumalaikolundusubramanian
Keywords
Related Articles
- EP ID EP344928
- DOI 10.9734/BJPR/2014/9961
- Views 70
- Downloads 0
Simultaneous Estimation of Luteolin and Apigenin in Methanol Leaf Extract of Bacopa monnieri Linn by HPLC
Aims: To develop, validate and quantify the content of flavonoids luteolin and apigenin in aerial parts of methanol leaf extract of Bacopa monnieri (B. monnieri) by reverse phase liquid chromatography. Study Design: High...
Tricyclic Pyrazoles: Synthesis, Characterization, Antimicrobial, Antituberculosis, and Antitumor Activity of N,1-Diphenyl-1,4-dihydrothiochro-meno[4,3-c]pyrazole-3-carboxamide-5,5-dioxide Derivatives
Aims: A series of N,1-diphenyl-1,4-dihydrothiochromeno[4,3-c]pyrazole-3-carboxamide 5,5-dioxide derivatives (6a-m) were synthesized and evaluated for anticancer, antibacterial, and antifungal activity. Methodology: React...
Development and Validation of Densitometry TLC Stability Indicating Method for Quantitative Determination of Azelastine Hydrochloride and Emedastine Difumarate in Their Drug Products
Aims: Stability indicating densitometry-TLC assay was established and validated for determination of azelastine hydrochloride (AZT) and emedastine difumarate (ETD) in the presence of their acid and oxidative degradants....
Influence of Process Parameters on Compressibility, Solubility and Release Characteristics of Melt Sonocrystallized Fenofibrate
Aims: The aim of the present study was to investigate the suitability of the melt sonocrystallization (MSC) technique to modify the processability properties along with solubility and drug release of anti-hyperlipidemic...
Formulation and Characterization of Nystatin-loaded Nanostructured Lipid Carriers for Topical Delivery against Cutaneous Candidiasis
Aims: The objective of the current study was to formulate nystatin (Nyst) into nanostructured lipid carriers (NLCs) to enhance its antifungal activity. Place and Duration of Study: Department of pharmaceutical technolog...