Assessment of autonomic dysfunction in bronchial asthma patients
Journal Title: Indian Journal of Clinical Anatomy and Physiology - Year 2018, Vol 5, Issue 4
Abstract
Introduction Many aspects of airway functions are controlled by autonomic nerves Bronchospasm airway edema and excessive mucus secretion may occur due to abnormality in autonomic regulation of airways All these events lead to airway obstruction in bronchial asthmaObjective The aim of the study was to compare the autonomic functions between bronchial asthma patients and normal controlsMaterials and Methods As per American Thoracic Society guidelines thirty bronchial asthma patients in the age group of 1850 years were chosen Thirty age and sex matched controls were chosen for comparison Standardized autonomic function tests were done Statistical analysis was done using students unpaired t testResults Significantly higher basal heart rate was found in asthmatics in comparison with controls Parasympathetic function tests showed significantly higher values in asthmatics compared with controls Statistically significant difference is also found in the sympathetic function tests between asthmatics and normal controlsConclusion Our study shows that autonomic dysfunction is present in asthmatic patients Parasympathic activity is enhanced in asthmatics thus supporting the hypothesis of enhanced parasympathetic reactivity as an integral factor in pathophysiology of bronchial asthma Keywords Bronchial asthma Autonomic dysfunction Parasympathetic tests Sympathetic tests
Authors and Affiliations
Mohammed Jaffer, Raghavendra Sherikar, Shivakumar J, Usha Sherikar
Keywords
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- EP ID EP476131
- DOI 10.18231/2394-2126.2018.0121
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