Assessment of Gall Bladder Mucosal Changes in Gallstone Patients Undergoing Laparoscopic Cholecystectomy: A Pathologic Study
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 5
Abstract
Background: Cholelithiasis is seven times more common in North India with an overall incidence of about 2.29%. Discarding gallbladder specimens without histopathological analysis is best avoided. Hence; present study was planned to assess gall bladder mucosal changes in gallstone patients undergoing laparoscopic cholecystectomy. Materials & methods: A total of 100 gallstone patients were analyzed in the present study. Serum biochemical profile of all the patients was obtained. All the patients underwent Laparoscopic cholecystectomy under the hands of skilled surgeons. Gallbladder mucosal samples were obtained and were sent for histopathologic analysis. H and E stained slides were made and were analyzed by skilled and experienced pathologists. All the results were recorded and analyzed by SPSS software. Results: Chronic calculous cholecystitis was found to be present in 88 cases, while malignancy was found to be present in 8 cases. Malignant diagnosis was found in 8 patients, while non- malignant diagnosis was present in 92 patients. Non-significant results were obtained while correlating the type of pathology with age-wise distribution of patients. Conclusion: A significant correlation might exist in between the spectrum of histologic alterations in the gallbladder mucosa and the pathogenesis of gallstone formation.
Authors and Affiliations
Neeta Agarwal
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