ASSESSMENT OF RENAL DYSFUNCTION IN CHRONIC LIVER DISEASES
Journal Title: IJSR-International Journal Of Scientific Research - Year 2018, Vol 7, Issue 3
Abstract
Objectives: Renal impairment in Patients with chronic liver disease is a common phenomenon and is a functional impairment. It seems difficult for the assessment of renal function abnormalities by normal parameters. We aimed to determine the usefulness of creatinine clearance by timed urine collection and Cockcroft Gault formula and Serum creatinine as parameters in assessing renal function in this cohort of patients and also to find if etiology of chronic liver disease has a bearing on renal dysfunction. Material and methods: Renal parameters of 200 patients with chronic liver disease were studied to assess the reliability of the each parameter. Results: In the present study, Only 22% of alcoholics have clearance more than 60ml/min. 58% patients were found to have creatinine clearance more than 60ml/min by Cockcroft Gault formula while only 36% Patients have that by timed urine collection where the difference was found to be statistically significant (P value<0.01). Cockcroft Gault formula overestimates probably due to disparity in weight due to fluid retention. Conclusion: The most reliable Parameter in our clinical setup is Creatinine clearance by timed urine collection. Presence of Ascites, low serum albumin levels and Alcoholic etiology had more predisposition to renal impairment, however, a larger study with more number of patients can throw more light.
Authors and Affiliations
Dr Prahallad Chandra Mishra, Dr Kamal Lochan Behera, Dr Pilla Rakesh, Dr Bh V K Praveen Varma, Dr Aswini Kumar Sahoo
Keywords
Related Articles
- EP ID EP506438
- DOI -
- Views 66
- Downloads 0
Life and Death of PARTHIV SHARIRA
Life consists of three components: 1. JIVATMA, 2. PRANA, 3. MANA. In a living PARTHIV SHARIRA JIVATMA is present in the form of heart beat, PRANA is present in the form of respiration and MANA is present in the form of f...
LAPAROSCOPIC MANAGEMENT OF LIVER HYDATID DISEASE
Background: Hydatid disease is a zoonosis produced by the larval stage of Echinococcus granulosus, with an endemic distribution, mainly in the rural areas. The management of Hydatid disease includes medical treatment wit...
EFFECT OF HOSPITAL PROTOCOL IMPLEMENTATION, ENFORCEMENT, AND PERFORMANCE IMPROVEMENT TRACKING ON OUTCOMES IN HIP FRACTURE PATIENTS
Introduction: Hip fractures are increasingly common injuries encountered by trauma surgical services. Risk of morbidity and mortality associated with such injuries may be dependent on the standardization of clinical care...
A HOSPITAL BASED STUDY ON NEONATAL OUTCOME IN MONOCHORIONIC AND DICHORIONIC TWIN PREGNANCIES
Background: Twin pregnancies account for 2 to 4% of the total number of births. Twin pregnancies are associated with signicantly higher morbidity and mortality than are singleton pregnancies. Among the twin pregnancies,...
Astigmatic Profile Induced by Superior Vs. Temporal Clear Corneal Incision in Phacoemulsification
Aim:To analyze the postoperative astigmatism after phacoemulsification and intraocular lens implantation through a superior vs. temporal clear corneal incision. Methods: This prospective observational study included 85 p...