Assessment of Salivary Interleukin-1 Receptor Antagonist and Obesity Measures of Patients with Chronic Periodontitis in Comparison to Healthy Control
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2017, Vol 6, Issue 9
Abstract
Aim: To measure BMI and waist circumference (WC) of patients with chronic periodontitis as well as healthy control, and to correlate these measurements with the clinical periodontal parameters, also to assess the level of salivary IL-1Ra of patients with chronic periodontitis in comparison to healthy control, to correlate the level of this marker with the clinical periodontal parameters and with anthropometric measurements (BMI and WC). Materials and Methods: Ninety subjects including both males and females with age between 35-55 years participated in this study. They were divided into two groups: Group 1 was chronic periodontitis (CP) group and it consist of 55 subjects and the Group 2 consist of 35 subjects as control group as they were with healthy periodontium and systemically healthy. Anthropometric measurements were measured for all participants, the whole unstimulated salivary sample was collected, and then periodontal evaluation that including the assessment of clinical periodontal parameters were done for all participants. ELISA was used to determine the level of IL-1Ra in saliva. Results: The results revealed a nonsignifcant difference between the two groups regarding the BMI, while showed that there was a signifcant difference in WC between the two groups, that the mean value of WC was higher in chronic periodontitis group than the control group. Regarding the salivary level of IL-1Ra it was revealed that the mean value of salivary level of IL-1Ra was statistically higher in chronic periodontitis group than the control group and there was a highly signifcant difference between them. According to Pearson Correlation, this study showed that there is a strong positive correlation between clinical periodontal parameters (GI, BOP, PPD, and CAL) with BMI and WC. This study also revealed that there is a strong positive correlation between clinical periodontal parameters with salivary level of IL-1Ra. Also, it showed a strong positive correlation between salivary level of IL-1Ra with BMI and WC. Conclusion: This study offers evidence of relationship between clinical periodontal and obesity parameters therefore one condition may act as a risk factor for another as well as it showed relationship between salivary IL-1Ra and periodontal/obesity measures.
Authors and Affiliations
Ali Baidaa T| Master Student, Department of Periodontology, College of Dentistry, University of Baghdad, Iraq, Corresponding e-mail: baidaa812@gmail.com, Mahmood Maha SH| Professor, Department of Periodontology, College of Dentistry, University of Baghdad, Iraq
Keywords
Related Articles
- EP ID EP12460
- DOI -
- Views 334
- Downloads 14
Understanding Clinical Signifcance of GPI Anchored Proteins in Mammalian System: Special Emphasis on Genetic Disorders of GPI Anchor Biosynthesis Pathway
The mode of attaching the membrane protein with GPI anchor is known as GPI anchoring of protein and proteins thus formed are known as GPI anchored protein. GPI anchor is a glycolipid moiety which is synthesized in endop...
A COMPARATIVE STUDY ON LIFESTYLE AND METABOLIC PROFILE IN NORMAL AND OBESE INDIVIDUALS
Background/Aim: The aim of the present study was to evaluate the lifestyle and metabolic profiles in normal and obese. Material and Methods: A cross sectional study design was employed. Information on body weight, heig...
Tumour Induced Osteomalacia: An Often-Missed Cause of Chronic Hypophosphatemia
Signifcant hypophosphatemia in adult is uncommon, in which the most common culprit being Vitamin D defciency. Hypophosphatemia in adults, require proper attention as it may indicate paraneoplastic effect of mesenchymal...
HYPERSENSITIVITY TO LIGNOCAINE: A CASE REPORT
Local anaesthetics are a very important group of drugs in the anaesthetists’ armamentarium. They have very widespread use in many branches like surgery, Orthopaedics, ENT, Obstetrics & Gynaecology. Most popular amide...
Static and dynamic cyclotorsion measurement and evaluation of related factors in patients candidates for PRK
To evaluate the degree of static and dynamic cyclotorsion and related factors in patients candidate for photorefractive keratectomy. In this analytic-descriptive study, 400 patients (aged 18-55 years) who were candidat...