Assessment of Salivary Lactate Dehydrogenase Activity in Oral Squamous Cell Carcinoma
Journal Title: GUJARAT CANCER SOCIETY RESEARCH JOURNAL - Year 2017, Vol 19, Issue 2
Abstract
Oral cancer is a major health burden in India. Therefore, it is important and necessary to apply the vast knowledge about salivary biomarkers for screening of oral cancer. Hence, aim and objective of the study were to evaluate salivary lactate dehydrogenase (LDH) and its isoenzyme activities in healthy individuals and oral cancer patients. Blood and saliva samples were collected from 20 healthy individuals and 25 oral cancer patients. Total LDH activities from serum and saliva samples of the subjects were analyzed by spectrophotometric method. Isoenzymes of LDH were separated using polyacrylamide gel disc electrophoresis and gels were analyzed using densitometer. Statistical analyses were carried out by SPSS software (version 15)
Authors and Affiliations
Jayendrakumr B Patel, Kinjal R Patel, Shruti R Patel, Kinjal D Patel, Prabhudas Patel
Keywords
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