Assessment of Urea, Creatinine, Calcium and Magnesium among Drug Users Homeless –Khartoum
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 11
Abstract
Background: Homeless is worldwide problem, developed and under-developed countries are suffering from, rises leading to health problem, drugs and alcohol related , lack to engage and to medical care, so they develop chronic disorders and that rises morbidity and mortality.. Objective: The aim of this study to evaluate the levels of urea, creatinine, calcium, magnesium and urea/creatinine ratio in homeless individual ,and the effect of the drugs abuse on measured parameters.. Materials and Methods: 50 drugs abuse homeless members were volunteer to assess urea, creatinine, urea /creatinine ratio, calcium and magnesium .In addition 50 healthy controls were involved. Parameters were measured by means of semi – automated chemical analyzer BTS 350, using Biosystem reagents, data obtained analyzed via statistical pakage of social version 22. Results: The level of serum creatinine and urea was significantly increased in drugs abuse homeless group when compared with reference group (0.56±0.23 mg/dl versus 0.93±0.19) (P 0.5). Also the urea creatinine ratio was significantly higher in drugs abuse homeless group when compare with health control (49.9±29.15 mg/dl versus 24.56±8.77) (P = 0.000).The study illustrated significant decrease in the level of both calcium and magnesium in drugs abuse homeless group when compared with reference group (8.62±0.53mg/dl versus 9.53±0.67.mg/dl p= 0.000, 2.196±0.37mg/dl versus 1.97±0.40 mg/dl p= 0.005 respectively). Across the gender the study deduced significant difference in urea and creatinine levels (male 27.40 ±2.74 mg/dl female 21.11±2.49 mg/dl p =0.002, male 0.97±0.04 female 0.51±0.02mg/dl p= 0.027 respectively) where as there is insignificant difference in calcium and magnesium levels (p ≥ 0.05) in the drugs abuse homless group. Furthermore the levels of creatine and urea were significantly positively correlated with duration of drugs abuse homless (p<0.05), where as calcium and magnesium levels were significantly inversely correlated with duration of drugs abuse homless in the study group(p< 0.05). Across the gender urea and creatinine were significantly differ (p < 0.05) where as there is insignificant difference in calcium and magnesium levels (p > 0.05) in the drugs abuse homless group. Conclusion: Substances abuse by homeless significantly impairs the renal function and decreased calcium and magnesium levels, so they should be considered as risk factors for kidney injury and osteoporosis among homeless.
Authors and Affiliations
Suhair A. Ahmed
Keywords
Related Articles
- EP ID EP507212
- DOI -
- Views 71
- Downloads 0
Intra-Medullary Spinal Cord Metastasis of Ovarian Carcinoma: A Rare Case Report
Ovarian carcinomas metastasizing to the spinal cord are infrequent. Incidences of isolated metastatic deposits of ovarian carcinoma to spinal medulla have rarely been reported. We present a case of a 74 year old woman wh...
Wilson Disease Presenting with Amenorrhea and Normal Urinary Copper Levels
Wilson’s disease (WD) or hepatolenticular degeneration is an inherited autosomal recessive disease characterized by a defect in the biliary copper excretion, leading to copper accumulation in many organs. The absence of...
The use of cerebrospinal fluid C reactive protein and adenosine deaminase as diagnostic markers in differential diagnosis of meningitis
Meningitis is an important public health problem in developing countries with considerable morbidity and mortality. Early categorisation according to the aetiology of meningitis leads to specific treatment with better ou...
Profile of Multidrug Resistant Acinetobacter Baumannii Infections among Hospitalized Patients
Background: Infections by Acinetobacter baumanniiis posing serious healthcare-associated infections [HAIs] and the incidence is increasing, with many strains now being multidrug resistant [MDR]. MDR Acinetobacter baumann...
A Study to Assess Treatment response and Pattern among Lung Cancer Patients in a Tertiary Care Hospital of India
Introduction: Lung cancer is among the five main types of cancer leading to overall cancer mortality contributing about 1.3 million deaths/year globally. There are only few Indian studies on bronchogenic carcinoma in pat...