Assessment of Vitamin D Level in Patients of Alopecia Areata

Journal Title: Journal of Clinical and Investigative Dermatology - Year 2016, Vol 4, Issue 2

Abstract

Alopecia Areata (AA) is a T cell-mediated autoimmune disease that causes inflammation around anagen-stage hair follicles. Insufficient levels of vitamin D have been implicated in a variety of autoimmune diseases. Previous reports have described the effects of vitamin D on hair follicles. To evaluate the status of vitamin D in patients with AA, and the relationship between vitamin D levels and disease severity, a cross-sectional study of 23 patients with AA and 23 healthy controls was conducted. Serum vitamin D levels of the study group were determined by ELISA technique. Results revealed a significant difference between cases and control as regards 25(OH) vitamin D level and its status. There is also a significant difference between 25(OH) vitamin D status and the degree of AA but not with the pattern of AA. However, there is a non-significant difference in the 25(OH) vitamin D status in all participants regarding age and sex of subjects. Accordingly, screening patients with AA for vitamin D deficiencies seems to be of value for the possibility of supplementing these patients with vitamin D.

Authors and Affiliations

Abdallah H Kandil

Keywords

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  • EP ID EP239833
  • DOI 10.13188/2373-1044.1000030
  • Views 66
  • Downloads 0

How To Cite

Abdallah H Kandil (2016). Assessment of Vitamin D Level in Patients of Alopecia Areata. Journal of Clinical and Investigative Dermatology, 4(2), 1-4. https://europub.co.uk./articles/-A-239833