Association between bronchial asthma in atopic children and their number of siblings
Journal Title: Paediatrica Indonesiana - Year 2014, Vol 54, Issue 5
Abstract
Background The prevalence of asthma in children has increased in many countries. Environmental factors are believed to play an important role and an inverse relationship between number of siblings and atopic disorders has been observed.Objective To assess for an association between bronchial asthma in atopic children and their number of siblings.Methods A cross-secrional study was conducted from June to November 2010 in three elementary schools in Medan, North Sumatera. Trace cards from the Allergy-Immunology Indonesian Pediatric Association (IDAI) Working Group and questionnaires on the clinical history of atopy were used to screen children with the risk of atopy. The International Study of .Asthma and Allergies in Childhood (ISAAC) questionnaire to screen for bronchial asthma was distributed to children aged 7-10 years with a history of asthma, allergic rhinitis or atopic dermatitis. Subjects were divided into two groups, those with <3 siblings and those with 2:3 siblings. Chi-square test was used to analyze differences in bronchial asthma prevalence between the two groups.Results Ninety-six subjects enrolled in the study, with 48 subjects per group. The prevalence of bronchial asthma was significantly higher in atopic children who had <3 siblings than in children with 2:3 siblings (73.5% and 26.5%, respectively; P=0.04).Conclusion Bronchial asthma was significantly more frequent in children with less than 3 siblings compared to those with 3 or more siblings.
Authors and Affiliations
Johan Siregar, Lily Irsa, Supriatmo Supriatmo, Sjabaroeddin Loebis, Rita Evalina
Keywords
Related Articles
- EP ID EP458746
- DOI 10.14238/pi54.5.2014.289-93
- Views 93
- Downloads 0
Ferric sodium edetate therapy in children with iron deficiency anemia
Background Iron deficiency anemia (IDA) is frequentlyfound in school-aged children. The main treatments for IDAare overcoming the causal factors and iron supplementation.Noncompliance in taking iron tablets and the possi...
The accuracy of a clinical parameters-based scoring system to predict spontaneous intracranial hemorrhage in children under one year old
Background Previous studies show that most children aged less than 1 year had intracranial hemorrhage without any history of trauma. The sign and symptoms of spontaneous intracranial hemorrhage (SIH) in children varies....
Quantitative NS1 antigen and the severity of dengue virus infections
Background Dengue infection is one of the main cause ofmorbidity and mortality in children in Indonesia. Since it is knownthat earlier treatment and supportive therapies can decreased casefatality rate from dengue hemorr...
Congenital obstructive posterior urethral membranes and recurrent urinary tract infection: a rare case of congenital hypertrophy of the verumontanum
Congenital obstructive posterior urethral membranes (COPUM) is a complex disease closely related to several pathological changes in kidney development and function, as a result of urinary reflux since in utero. This cong...
Puberty onset in rural and urban children
Background Accelerated pubertal onset has been reported in recent years. Environmental factors are assumed to influence this condition.Objective To assess differences in pubertal onset between children in rural and urban...