Association between Glycated haemoglobinand Serum Lipid Profile in Type 2 Diabetic Patients in Kumaun Region, Uttarakhand
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 3
Abstract
Type 2 diabetes is known to have increased prevalence of lipid abnormalities leading to high risk of cardiovascular diseases (CVD). Diabetic patients are at more risk for altered lipid profile than normoglycemic persons. Glycated hemoglobin (HbA1c) is a routinely used marker for long-term glycemic control and as a screening tool for the diagnosis of diabetes. A value over 6% gives an indication of altered glucose control. Also, HbA1c nowadays is considered an independent risk factor for CVD. In this study association between Glycated haemoglobin (HbA1c) and diabetic dyslipidemia was found. Venous blood samples were collected from 113 type 2 diabetic patients. The whole blood and serum were analyzed for HbA1c, fasting blood sugar (FBS) and lipid profile using cobas c 501 system. The statistical analysis was done by SPSS statistical package version 21. HbA1c showed significant correlations with total cholesterol (TC), triglycerides (TG), low density lipoprotein cholesterol (LDL-C) and TC/HDL-C ratio. Patients with HbA1c value > 7.0% had significantly higher value of TC, Triacylglycerol (TG), VLDL-C, LDL-C and TC/HDL-C ratio as compared to the patients with HbA1c ≤ 7.0%. However, there was no significant difference in value of HDL-C between two groups. Thus,HbA1c can be used as a potential biomarker for predicting dyslipidemia in type 2 diabetic patients.
Authors and Affiliations
Dinesh Bure
Keywords
Related Articles
- EP ID EP507950
- DOI -
- Views 64
- Downloads 0
MRI Diagnosis in Children with Global Developmental Delay
Aim and objective: To determine the prevalence of abnormal brain MRI in children aged 2 mon to 12 yrs with Global developmental delay. Methods: This is a prospective observational study where a total of 42 children aged...
Comparative Study of Epidural Dexmedetomidine with Clonidine as Adjuvant to Isobaric Ropivacaine in Abdominal Hysterectomy
Background: Aim of the study was to compare epidural α2 adrenergic agonists, Dexmedetomidine and Clonidine as adjuvant to Isobaric Ropivacaine with respect to block characteristics, postoperative analgesia, sedation and...
Role of Imprint Cytology in the Diagnosis of Malignant Lesions- A Hospital Based Study
Background: Imprint cytology is a simple, cost effective and rapid procedure for the diagnosis of various malignant lesions. However histopathological examination remains the gold standard for the diagnosis of the malign...
Study the Effect of Hydrogen Peroxide and Alpha Lipoic Acid on Wound Healing in Rabbits
The aims of this study was to compare between the effect of hydrogen peroxide (oxidant) and lipoic acid (Antioxidant) on wound healing in rabbits. Fifteen adult healthy rabbits were used. It is divided in to three groups...
Plasmodium vivax Detected on Anophles punctulatus Using ELISA: A Vector Confirmation Study in Tamraw District, A Remote Area With High Incidence of Malaria, West Papua Province-Indonesia
Background: Tamraw District is a new administrative district of West Papua Province with high incidence rate of malaria. The aim of the study was to detect Plasmodiumsp in Anophelessp using ELISA assay in Tamraw District...