Association between hypovitaminosis D and diabetic retinopathy in type II diabetes mellitus
Journal Title: Medpulse International Journal of Ophthalmology - Year 2019, Vol 9, Issue 2
Abstract
Background: Diabetes mellitus is associated with considerable morbidity and mortality with its prevalence increasing every year. Vitamin D plays an important role in calcium metabolism and vitamin D deficiency is associated with many diseases, including cancer, cardiovascular disease, and type 2 diabetes mellitus. The studies showing the effect of vitamin D on diabetic retinopathy are controversial and have shown inconclusive results. So there is the need to study the effect of vitamin D on diabetic retinopathy in patients with type 2 diabetes mellitus. Aims and Objectives: To quantitatively estimate the levels of vitamin D in serum and assess diabetic retinopathy in cases and controls. To find the association between status of Vitamin D and diabetic retinopathy in type 2 Diabetes mellitus. Materials and Methods: This study was conducted in department of Ophthalmology Gadag Institute of medical sciences Gadag, Karnataka. 50 patients with diabetic retinopathy were compared with 50 patients with diabetes and without diabetic retinopathy after taking an informed consent. Vitamin D was estimated by Chemiluminescence Immuno Assay (CLIA ) method. Retinopathy was assessed using indirect ophthalmoscopy fasting and post prandial blood sugar was estimated by GOD-POD method. Results: vitamin D (p=0.015) was highly significant in patients with diabetic retinopathy as compared with diabetics without retinopathy. The study showed a negative correlation between vitamin D and diabetic retinopathy. Conclusion: Decreased vitamin D levels are statistically highly significant in diabetic retinopathy. Hypovitaminosis D is negatively correlated with diabetic retinopathy.
Authors and Affiliations
Gajanan D Channashetti
Keywords
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- EP ID EP536217
- DOI 10.26611/1009926
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1. "Facts About Cataract". September 2009. Archived from the original on 24 May 2015. Retrieved 24 May 2015. 2. "Visual impairment and blindness Fact Sheet N°282". August 2014. Archived from the original on 12 May 2015. Retrieved 23 May 2015 3. Blindness in the elderly [editorial]. Lancet. 2008; 372: 1273. 4. National Program for Control of Blindness in India, Directorate General of Health Service
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