Association between hypovitaminosis D and diabetic retinopathy in type II diabetes mellitus
Journal Title: Medpulse International Journal of Ophthalmology - Year 2019, Vol 9, Issue 2
Abstract
Background: Diabetes mellitus is associated with considerable morbidity and mortality with its prevalence increasing every year. Vitamin D plays an important role in calcium metabolism and vitamin D deficiency is associated with many diseases, including cancer, cardiovascular disease, and type 2 diabetes mellitus. The studies showing the effect of vitamin D on diabetic retinopathy are controversial and have shown inconclusive results. So there is the need to study the effect of vitamin D on diabetic retinopathy in patients with type 2 diabetes mellitus. Aims and Objectives: To quantitatively estimate the levels of vitamin D in serum and assess diabetic retinopathy in cases and controls. To find the association between status of Vitamin D and diabetic retinopathy in type 2 Diabetes mellitus. Materials and Methods: This study was conducted in department of Ophthalmology Gadag Institute of medical sciences Gadag, Karnataka. 50 patients with diabetic retinopathy were compared with 50 patients with diabetes and without diabetic retinopathy after taking an informed consent. Vitamin D was estimated by Chemiluminescence Immuno Assay (CLIA ) method. Retinopathy was assessed using indirect ophthalmoscopy fasting and post prandial blood sugar was estimated by GOD-POD method. Results: vitamin D (p=0.015) was highly significant in patients with diabetic retinopathy as compared with diabetics without retinopathy. The study showed a negative correlation between vitamin D and diabetic retinopathy. Conclusion: Decreased vitamin D levels are statistically highly significant in diabetic retinopathy. Hypovitaminosis D is negatively correlated with diabetic retinopathy.
Authors and Affiliations
Gajanan D Channashetti
Keywords
Related Articles
- EP ID EP536217
- DOI 10.26611/1009926
- Views 89
- Downloads 0
Study of indication of destructive ocular surgeries at Sagarmatha Choudhary eye hospital, Lahan
Background: To determine the indications for destructive ocular surgery in our hospital so that it would be useful in planning strategies and to reduce avoidable eye loses and associated challenges after destructive ocul...
A comparative assessment of voriconazole vs natamycin in treatment of mycotic corneal ulcer
Background: Mycotic corneal ulcer is endemic in tropical regions accounting for as many as half of corneal ulcers. Management of fungal keratitis requires timely diagnosis of the infection and administration of appropria...
Bacteriological flora of conjunctiva among pregnant women
Background: Normal microbial flora of eye constitutes organisms which are present on eyelids and conjunctiva without causing any disease. Various factors alter the conjunctival flora such as, seasonal variations, tempera...
Nondecussating retinal-fugal fiber syndrome: Case report of a rare cause of congenital nystagmus
Congenital nystagmus is a condition presenting itself in neonatal period or early infancy and Persists throughout the life. The overall prevalence of nystagmus is reported to be between 2-3 cases per 10000 individuals. I...
Comparison between suturless and glue free aminotic membrane graft versus suturles limbal conjunctival autograft in primary pterygium
Aim: To compare the outcome of primary pterigium excision with amniotic membrane and conjunctival auto graft. Methods: This study was carried out in the premises of rural-based tertiary hospital, A comparative prospectiv...